The oLIVER team identified potential biomarkers and drug targets for metabolic dysfunction-associated steatotic liver disease (MASLD) using a new approach called APTASHAPE. This approach uses billions of different small RNA biosensors to generate digital "fingerprint pictures" of blood plasma samples. As the oLIVER project focused on liver disease, the team compared samples from patients with samples from healthy controls. In this way, the oLIVER team identified discrete "fingerprint pictures" that are relevant for both diagnosis and prognosis of liver disease.
On this page you can can watch a video recorded at the beginning of the oLIVER project. You can also read an article on the output of the project or read a short cartoon story about the aim of the project.
We unite bright minds from industry and academia to jointly create need-driven clinical research projects - and pave the way for innovative new treatments and diagnostics. We fund the best project ideas through competitive funding calls. Although companies cannot receive funding, it is free of charge to join.
The platform is sponsored by the Novo Nordisk Foundation with 180 million DKK from 2024-2029.
You are welcome to contact us if you have questions or comments. Reach out to odin@au.dk or find the Secretariat's direct email addresses under contacts.
Although the platform spans five Danish universities, we're based in Aarhus. Our office is located at Aarhus University, Ny Munkegade 120, blg 1521-214.