08:30

Coffee and registration

09:00

Welcome by Poul Nissen (Dept. Molecular Biology and Genetics / DANDRITE)

09:10

Keynote lecture by Birthe B. Kragelund (Department of Biology, University of Copenhagen)

Title: "Understanding Disordered Proteins Complexes by Integration"

09:35

Inspirational talk by Lucy Holt (Department of Biology, University of Copenhagen)

Presentation of ISBUC (Integrative Structural Biology at University of Copenhagen)

SESSION I - HIGHER ORDER STRUCTURE AND THE CELL

Chair: Rune Hartmann

09:55

Thomas Vorup-Jensen (Dept. Biomedicine): “Protein Aggregates and Inflammation”

10:10

Thomas L-M Sørensen (Dept. Biological and Chemical Engineering): “Organoids and Imaging”

10:25

Robert Fenton (Dept. Biomedicine): “Systems biology of Slc12 transporters - from mouse to man”

10:40

Tobias Weidner (Dept. Chemistry): “Structural biology at interfaces”

11:00

Fulvio Reggiori (Dept. Biomedicine): “Autophagy in Health and Disease”

11:20

Lunch and poster session (with prepared 2 min short-talks in front of posters)

SESSION II - EXPERIMENTAL STRUCTURE DETERMINATION

Chair: Esben Lorentzen

12:45

13:00

Henrik Birkedal (Dept. Chemistry): “Hierarchical biological structures by multiscale and multimodal X-ray imaging”

Bjørn Pedersen (Dept. Molecular Biology and Genetics): “Molecular mechanisms of proton-driven transmembrane transport”

13:15

Poul Nissen (Dept. Molecular Biology and Genetics/DANDRITE):  “Cryo-EM studies of mammalian membrane transporters”

13:30

Joseph Lyons (Dept. iNANO): “Structural and functional characterisation of lipid transport and metabolism systems”

13:45

Ditlev Brodersen (Dept. Molecular Biology and Genetics): “Understanding the molecular mechanisms of bacterial survival and immunity”

14:00

Daan van Aalten (Dept. Molecular Biology and Genetics): “Molecular mechanisms of O-GlcNAc signalling”

14:15

Mette Galsgaard Malle (postdoc in Jørgen Kjems group, iNANO)

(CANCELLED: Christian Brix Folsted Andersen (Dept. Biomedicine): “Structure and function of endocytic receptors”)

14:35

Coffee and cake break

SESSION III - INFRASTRUCTURE AND FACILITIES

Chair: Poul Nissen

15:00

Thomas Boesen (Dept. iNANO): “The EMBION National Cryo-EM Facility”

15:15

Michael Westberg (Dept. Chemistry): "Protein Design, Binders, and Photoactive Domains: Characterization and Application"

(CANCELLED: Søren Vrønning Hoffmann (Dept. Physics): “Synchrotron Radiation Circular Dichroism facilities at ASTRID2”)

SESSION IV - STRUCTURAL DYNAMICS

Chair: Ebbe Andersen

15:30

Victoria Birkedal (Dept. Chemistry): “Single molecule fluorescence imaging of nucleic acids and proteins”

15:45

Frans Mulder (Dept. Chemistry): “Measuring protein electrostatics by NMR spectroscopy”

16:00

Daniel Otzen (Dept. iNANO): “The Protein Biophysics group: from self-assembly to disassembly”

16:15

Jørgen Kjems (Dept. iNANO): “Engineering biological nanopores for sensing”

16:35

Break

SESSION V - COMPUTATIONAL METHODS AND MODELLING

Chair: Daniel Otzen

17:00

Birgit Schiøtt (Dept. Chemistry): “Complex membranes and how MD can provide insight in mechanism of membrane proteins”

17:15

Esben Lorentzen (Dept. Molecular Biology and Genetics): “Molecular mechanisms of cilium formation

17:30

Ebbe Andersen (Dept. iNANO): “Folding and flexibility of RNA nanostructures revealed by cryo-electron microscopy and tomography”

17:45

Jan Skov Pedersen (Dept. Chemistry): “Small-angle X-ray scattering for investigations of biomolecular complexes and for validation of EM maps”

18:00

Lili Zhang (Dept. Mechanical and Production Engineering): “Multi-Scale Methods to Extract Mechanical Properties from Molecular Dynamics Simulations”

18:15

18:30-19:30

Pizza and poster session