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"Open discovery of metabolic targets for therapeutic intervention in kidney disease"

The aim of the KidDO project was bipartite: First, the team identifed metabolites that can predict progression of chronic kidney disease (CKD). Second, they also studied how the interplay between metabolites and proeteins within the kidneys drive this progression.

The KidDO project (2021-2023) used both human CKD biopsies and rodent models and they identified a numer of metabolites and genes that were universially altered across all models in CKD. The KidDO team was multidisciplinary combining expertise within areas such as animal disease models, omics, computer science and drug delivery. The output of the project was the devleopment of a largescale database that can help researchers integrate metabolic and proteomic knowledge.

On this page you can can watch a video recorded at the beginning of the project. You can also read an article on the output of the project and you can find lists of project participants and articles published by the KidDO team.


Academic team members

  • Robert Fenton, Professor, Aarhus University
  • Ira Assent, Professor, Aarhus University
  • Markus Rinschen, Assoc. Professor, Aarhus University
  • Ken Howard, Assoc. Professor, Aarhus University
  • Qi Wu, Assoc. Professor, Aarhus University
  • Anja Billing, Assist. Professor, Aarhus University

Industrial team member

  • Pernille Lærkegaard Hansen, AstraZeneca

"Linking academic researchers with industry opens up new opportunities for collaborative research in kidney disease. The links to industry also provide a direct possibility for pharmaceutical exploitation of novel results.”


Robert Fenton, Head of the KidDO project

"We hope that the open approach will be valuable for researchers around the world as they can use our data for both model selection and they can also ‘cherry pick’ metabolites and proteins to examine in their own targeted research.”


Robert Fenton, Head of the KidDO project


We unite right minds from industry and academia so that they can jointly create need-driven research projects - and pave the way for innovative new treatments in the future. Through competitive funding calls, we fund the best projects ideas. Although companies cannot receive funding, it is free of charge to join.

The 5-year platform is sponsored by the Novo Nordisk Foundation with 180 M DKK from 2024-2028.


You are always welcome to reach out if you have questions or comments. Reach out to odin@au.dk or find the Secretariat's direct email addresses under contacts.

Although we're spanning five Danish universities, we're based in Aarhus. Our office is located at Aarhus University, Ny Munkegade 121, blg 1521-216.