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Fly Copulation. Credit: Philipsborn Research group
Graphical abstract: During copulation, males transfer not only sperm, but also seminal fluid. The authors hypothesize: Specific components of the male accessory gland secondary cells - secondary cell products (SCPs) cause the female to start singing. Her singing in turn prompts the male to allocate his ejaculate differently, ultimately giving him a reproductive advantage over other males, by biasing the female to mate with the next male later. Credit: Peter Kerwin, PhD-student, Philipsborn group

2020.03.19 | Publication, Knowledge exchange

Do your neighbours have a noisy love life? Consider yourself lucky that you are not a fruit fly! Anne von Philipsborn’s group has discovered that female fruit flies sing by pulsed wing vibrations while they are copulating.

The new study, published yesterday in Nature Communications, was led by experts in behavioural genetics and circuit neuroscience in Drosophila at DANDRITE. The researchers’ findings on Drosophila sexual behaviour are important for understanding the complexity of neurocircuitry and behavioural genetics. In this article, first author of the paper…

The graphical abstract shows the signalling pathways involved in cell death following treatment with the ER stressor thapsigargin. Credit: Lindner et al. 2020

2020.03.04 | Publication, Knowledge exchange, People

A recent publication by NCMM studied how the ER stressor drug thapsigargin and analogues for cancer-related therapies induce cell death in human cancer cells.

A recent publication by Lindner et al. entitled; “Cell death induced by the ER stressor thapsigargin involves death receptor 5, a non-autophagic function of MAP1LC3B, and distinct contributions from unfolded protein response components” studied how the ER stressor drug thapsigargin and analogues for cancer-related therapies induce cell death in…

Group leader Andrea Ganna. Credit: FIMM, University of Helsinki

2020.02.25 | People , Knowledge exchange

Introducing FIMM Group Leader Andrea Ganna

Andrea Ganna is a FIMM-EMBL Group Leader at the Institute for Molecular Medicine Finland at the University of Helsinki. He specializes in statistical genetics and epidemiology. In this article Andrea shares his research interests and explains how deep learning approaches and artificial intelligence can be used to leverage information from large…

The figure illustrates a proposed neural pathway that links the ON-OFF direction-selective (DS) cells in the retina (blue arrows) to the rostrolateral (RL) area. Credit: Rune N. Rasmussen

2020.02.13 | Publication, Knowledge exchange, Research news

Yonehara group discovers a new function of a specific type of retinal nerve cells and uncovers a nerve network that transmits visual information from retinal nerve cells into the cerebral cortex.

The new study, published this week in Nature Communications, was led by the neural circuitry team at DANDRITE. The researchers’ findings are important for understanding the mechanisms on how visual perceptions arise within the brain. In this article, first author of the paper, PhD-student at DANDRITE Rune Nguyen Rasmussen, sheds a light on their…

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