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The Danish Research Institute of Translational Neuroscience (DANDRITE) is the Danish node of the Nordic EMBL Partnership, and performs basic and translational research in brain and the nervous system.
The Institute for Molecular Medicine Finland (FIMM) is the Finnish node of the Nordic EMBL Partnership. FIMM’s research interests are human genomics and personalized medicine, with a focus on translational research.
The Laboratory for Molecular Infection Medicine Sweden (MIMS) is the Swedish node of the Nordic EMBL Partnership. MIMS aims to strengthen Swedish research and enhance the dynamics in the field of molecular medicine.
Centre for Molecular Medicine Norway (NCMM) is the Norwegian node of the Nordic EMBL Partnership. NCMM conducts molecular medicine & biotech research and works translate these findings into clinical practice.
The study used HDX-MS to map the epitope and paratope of the new high-affinity tumor-specific antibody developed against a variant of HER2. Antibodies directed against HER2 are already used in breast cancer therapy, and the new antibody developed by the collaboration has potential to be used as a diagnostic tool or future cancer treatment.
The so-called NKCC1 protein is found throughout the human body where it has important functions in organs that process fluids or perform neurotransmission. A Danish research team has now determined a three-dimensional atomic structure of the NKCC1 protein, which supports future work to identify novel compounds that interfere with NKCC1 function. Such compounds may help in, for example, kidney and brain disorders.
NCMM Group Leader Dr Emma Haapaniemi will collaborate with centre leaders and NCMM Associate Investigators Prof Johanna Olweus and Prof Karl-Johan Malmberg as part of the new centre, Precision Immunotherapy Alliance (PRIMA).
A Finnish-led international research team has discovered novel gene variants that increase the risk of a rare but severe lung disease, idiopathic pulmonary fibrosis. The results also demonstrate notable genetic similarities with susceptibility to severe COVID-19 infection.
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