Publications

Publications from PIG-PARADIGM

2026

Comparative study of cytokine measurements in blood plasma and serum, and saliva of juvenile pigs during experimentally induced acute inflammation

Pernille Aagaard Madsen,Kevin Jerez-Bogotá, Darya Vodolazska and Charlotte Lauridsen

Dietary iron and metal-based growth differentially modulate growth and gut microbiome of weaned piglets

Shya Navazesh, Anneliek ter Horst, Weizhang Wen, C. Titus Brown & Peng Ji

Dietary L-glutamate and L-aspartate improve growth, gut health, and amino acid digestibility in weaned piglets challenged with enterotoxigenic Escherichia coli

Wongchanla, S., Park, Y., Park, S., Sun, S., Zhao, Y., and Liu, Y.

Age-related remodeling of the intestinal mucus barrier in pigs: implications for post-weaning diarrhea

C.B. Becker, J. Elzinga, M.K. Morsing, C.B. Jørgensen, M. Fredholm, M.S. Hansen, S.S. Nielsen, J.P. Nielsen & H.E. Jensen

New Insights into Dietary L-Glutamate and L-Aspartate Modulation of Hematology, Immune Responses, and Metabolite Profiles in Enterotoxigenic Escherichia coli Challenged Piglets

Supatirada Wongchanla ,Sangwoo Park, Shuhan Sun, Peng Ji and Yanhong Liu

Comparative evaluation of post-mortem methods for detection of diarrhoea in early-life piglets

Cecilie Brandt Becker, Malene Kjelin Morsing, Julie Raundahl Laursen, Emma Amalie Kortemand Hansen, Jens Peter Nielsen, Merete Fredholm, Nicole Bakkegård Goecke, Mette Sif Hansen, Søren Saxmose Nielsen & Henrik Elvang Jensen

Dietary L-glutamate, L-aspartate, and their combination supplementation modulated hematological, immune, and metabolic responses in weaned piglets challenged with enterotoxigenic Escherichia coli

Wongchanla, S., Park, Y., Park, S., Sun, S., & Liu, Y.

Dietary iron and metal-based growth promoters differentially modulate the gut resistome and Escherichia coli virulome in weaned pigs

Shya E. Navazesh, Anneliek ter Horst, Weizhang Wen, Yanhong Liu, David Kiang, Zhirong Li, Alice Yu, C. Titus Brown & Peng Ji

Reducing antimicrobial resistance burden from livestock production by targeting pig gut health

Lauridsen C, Smidt H, Fredholm M, Marco ML and Arumugam M

Expanding the pig metabolomics QTL catalog

Ibragimov, E., Morsing, M.K., Rydal, M.P. et al.

2025

Outbreaks of post-weaning diarrhea caused by ETEC F4 are strongly associated with CHCF1 genotype in Danish pigs

Martin Peter Rydal, Kimmie Kyed Lyderik, Amanda Bastian Andersen, Claus Bøttcher Jørgensen, Peter Damborg & Jens Peter Nielsen

Effects of dietary L-glutamate and L-aspartate supplementation on growth performance, severity of diarrhea, intestinal barrier integrity, and fecal microbiota of weaned piglets challenged with F18 enterotoxigenic Escherichia coli.

Wongchanla, S., Dixit, K., Park, S. et al.

Temporal changes in biomarkers of oxidative stress and inflammation in pigs after intravenous administration of E. coli lipopolysaccharide

Pernille A. Madsen, Kevin J. Bogotá, Darya Vodolazska, Mette S. Hedemann, Andrew R. Williams, Charlotte Lauridsen

Genetic factors for hematological traits in pigs

Jiahong Sun, Emil Ibragimov, Peter Karlskov-Mortensen, Merete Fredholm

Machine-learning for quantitative histopathology of piglet intestinal tissues: challenges with limited training data

Becker CB, Hansen MS, Nielsen SS and Jensen HE

Iron Stress Reprograms Enterocyte Metabolism

Shya Navazesh & Peng Ji

Untargeted metabolomics as a tool to assess the impact of dietary approaches on pig gut health: a review

Chen, LH., Canibe, N., Curtasu, M.V. et al.

2024

Intestinal delivery of encapsulated bacteriocin peptides in cross-linked alginate microcapsules

Lei Wei, Dana Wong, Tina Jeoh, Maria L. Marco

Redox balance and immunity of piglets pre- and post-E. coli challenge after treatment with hemp or fish oil, and vitamin E

Madsen, P.A., Jensen, S.K. & Lauridsen, C.

Complete pipeline for Oxford Nanopore Technology amplicon sequencing (ONT-AmpSeq): from pre-processing to creating an operational taxonomic unit table

Schacksen, P.S., Østergaard, S.K., Eskildsen, M.H., Nielsen, J.L.

Modulating the gut microbiota in Crohn’s disease: a pilot study on the impact of a plant-based diet with DNA-based monitoring

Østergaard SK, Cetin Z, Rasmussen HH, Lærke HN, Holst M, Lauridsen C and Nielsen JL

Revised 23.10.2026

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Xi Song