First new publication from PIG-PARADIGM in 2026
The year is off to a fantastic start — we’re thrilled to share a new article from our researchers in the Nutrition Pillar!
Comparative study of cytokine measurements in blood plasma and serum, and saliva of juvenile pigs during experimentally induced acute inflammation by PhD Pernille Aagaard Madsen (AU), Kevin Jerez-Bogotá (Post Doc, AU) Darya Vodolazska (Post Doc, AU) & Charlotte Lauridsen.
This study investigated changes in concentrations of 13 cytokines in serum and saliva samples collected over a 72 h period following lipopolysaccharide (LPS) infusion. A strong positive correlation was observed between serum and EDTA plasma concentrations. In general, saliva did not correlate with serum for most cytokines, suggesting limited application of such a non-invasive matrix for systemic cytokine monitoring. However, IL-1α was detected at higher concentrations in saliva than in serum, suggesting that saliva may be useful for monitoring specific cytokines under certain inflammatory conditions. In conclusion, serum and plasma were suitable for cytokine analysis, while saliva may be useful for monitoring specific cytokines under certain inflammatory conditions.
Read the full article here