AUNAB - Aarhus University Network on Artificial Biology

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Recent research news on Artificial Biology

AUNAB is hosting an iGEM team to represent Aarhus University

- Research news

AUNAB has gathered a strong interdisciplinary team of 11 students across different educations, who will represent Aarhus University at the world's biggest synthetic biology competition, iGEM 2026. Read more about their process here.

Actin-Powered Motors Build Cytoskeletons in Artificial Cells

- Research news

AUNAB members Assistant Prof. Miguel Ramos Docampo's and Prof. Brigitte Stadler's effort to engineered artificial cells to form cytoskeleton-like networks using nanomotor-driven actin polymerization is published in ACS Nano. These hybrid vesicles merge active matter with synthetic biology to achieve life-like movement and self-organization inspired by Listeria’s actin-based propulsion.

 

Single Protein-Mediated Vesicle Division

- Research news

Steering group member of AUNAB, Prof. Brigitte Städler, has published a collaborative study in Advanced Materials on the successful reconstitution of the Drs2p–Cdc50p lipid flippase in polymer–lipid hybrid vesicles.

Technology Roadmap of Micro/Nanorobots

- Research news

Aunab steering group member, Prof. Brigitte Städler, is among 103 authors who contributed to this Mega Review published in ACS Nano on the topic of Micro/Nanorobots, a field that celebrated its 20th anniversary last year.

Transmembrane Activation of Catalysis and Protein Refolding in Synthetic Cells by Enzymes and Nanozymes

- Research news

The design of artificial cells is a focal point of intense research efforts. One characteristic that remains particularly hard to engineer is the responsive behavior in artificial cells. It requires the design of molecular mechanisms to receive, interpret, and react to external environmental or biochemical stimuli. This challenge is specifically addressed herein and the design of artificial cells that respond to the external chemical messenger by the activation of intracellular catalysis is…

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Recent publications by network

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Mahato, M., Hwang, W. J., Tabassian, R., Oh, S., Nguyen, V. H., Nam, S., Kim, J. S., Yoo, H., Taseer, A. K., Lee, M. J., Zhang, H., Song, T. E. & Oh, I. K. (2022). A Dual-Responsive Magnetoactive and Electro–Ionic Soft Actuator Derived from a Nickel-Based Metal–Organic Framework. Advanced Materials, 34(35), Article 2203613. https://doi.org/10.1002/adma.202203613
Zhu, X., Wang, Z., Gao, M., Wang, Y., Hu, J., Song, Z., Wang, Z. & Dong, M. (2022). AgPt/MoS2 hybrid as electrochemical sensor for detecting H2O2 release from living cells. New Journal of Chemistry, 46(31), 15032-15041. https://doi.org/10.1039/d2nj02495k
Yang, E., Metzloff, M., Langmüller, A. M., Xu, X., Clark, A. G., Messer, P. W. & Champer, J. (2022). A homing suppression gene drive with multiplexed gRNAs maintains high drive conversion efficiency and avoids functional resistance alleles. G3: Genes, Genomes, Genetics, 12(6), Article jkac081. https://doi.org/10.1093/g3journal/jkac081
Dinesen, A., Winther, A., Wall, A., Märcher, A., Palmfeldt, J., Chudasama, V., Wengel, J., Gothelf, K. V., Baker, J. R. & Howard, K. A. (2022). Albumin Biomolecular Drug Designs Stabilized through Improved Thiol Conjugation and a Modular Locked Nucleic Acid Functionalized Assembly. Bioconjugate Chemistry, 33(2), 333-342. https://doi.org/10.1021/acs.bioconjchem.1c00561
Fuchs, E., Rudnik-Jansen, I., Dinesen, A., Selnihhin, D., Mandrup, O. A., Thiam, K., Kjems, J., Pedersen, F. S. & Howard, K. A. (2022). An albumin-angiotensin converting enzyme 2-based SARS-CoV-2 decoy with FcRn-driven half-life extension. Acta Biomaterialia, 153, 411-418. https://doi.org/10.1016/j.actbio.2022.09.048
Dinesen, A., Winther, A., Wall, A., Märcher, A., Palmfeldt, J., Chudasama, V., Wengel, J., Gothelf, K. V., Baker, J. R. & Howard, K. (2022). An Albumin Biomolecular Drug Design Stabilized through Improved Thiol Conjugation and a Modular Locked Nucleic Acid Assembly. Poster session presented at Controlled Release Society 2022 Annual Meeting, Montreal, Quebec, Canada.
He, J., Steffen, J. H., Thulstrup, P. W., Pedersen, J. N., Sauerland, M. B., Otzen, D. E., Hawkins, C. L., Gourdon, P., Davies, M. J. & Hägglund, P. (2022). Anastellin impacts on the processing of extracellular matrix fibronectin and stimulates release of cytokines from coronary artery smooth muscle cells. Scientific Reports, 12(1), Article 22051. https://doi.org/10.1038/s41598-022-26359-9
Rajabi-Abhari, A., Lee, J., Tabassian, R., Kim, J.-N., Lee, H. & Oh, I.-K. (2022). Antagonistically Functionalized Diatom Biosilica for Bio-Triboelectric Generators. Small, 18(20), Article 2107638. https://doi.org/10.1002/smll.202107638
Ali, I. H., Ouf, A., Elshishiny, F., Taskin, M. B., Song, J., Dong, M., Chen, M., Siam, R. & Mamdouh, W. (2022). Antimicrobial and Wound-Healing Activities of Graphene-Reinforced Electrospun Chitosan/Gelatin Nanofibrous Nanocomposite Scaffolds. ACS Omega, 7(2), 1838-1850. https://doi.org/10.1021/acsomega.1c05095
Pirhaghi, M., Frank, S. A., Alam, P., Nielsen, J., Sereikaite, V., Gupta, A., Strømgaard, K., Andreasen, M., Sharma, D., Saboury, A. A. & Otzen, D. E. (2022). A penetratin-derived peptide reduces the membrane permeabilization and cell toxicity of α-synuclein oligomers. Journal of Biological Chemistry, 298(12), Article 102688. https://doi.org/10.1016/j.jbc.2022.102688

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Revised 03.03.2026
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Kalinka Hansen