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Recent research news on Artificial Biology

Receptor-Mediated Transmembrane Activation of Protein Folding in Synthetic Cells

- Research news

An article from the Zelikin lab just published in Bioconjugate Chemistry has been selected as the American Chemical Society Editor´s Choice (the one article chosen each day from the entire ACS portfolio to be highlighted for quality and/or broad interest).

Distinct Network Morphologies from In Situ Polymerization of Microtubules in Giant Polymer-Lipid Hybrid Vesicles

- Research news

Creating artificial cells with a dynamic cytoskeleton, akin to those in living cells, is a major goal in bottom-up synthetic biology. In this study, we demonstrate the in situ polymerization of microtubules encapsulated in giant polymer-lipid hybrid vesicles (GHVs) composed of 1,2-dioleoyl-sn-glycero-3-phosphocholine and an amphiphilic block copolymer. The block copolymer is comprised of poly(cholesteryl methacrylate-co-butyl methacrylate) as the hydrophobic block and either…

Cell Membrane Vesicle Camouflaged Artificial Cells

- Research news

The integration of artificial and mammalian cells into semi-synthetic aggregates remains a challenge in bottom-up synthetic biology. Here, the fabrication of cell membrane vesicles (CMV) from HepG2 cells and their use as a coating for alginate microgels to produce camouflaged artificial cells (ACs) is demonstrated. These ACs are used for the assembly of either synthetic aggregates or semi-synthetic aggregates. In the first case, a predator-defendant and a liver-like synthetic aggregates are…

Researchers propose a roadmap towards the synthesis of life

- Research news

A new perspective article by 57 international researchers, including Associate Professor Ebbe Sloth Andersen, outlines a roadmap for the synthesis of life. The paper explores key traits like resilience, sustainability, and evolution, and how synthetic life could revolutionize biotechnology, medicine, and materials science.

Single-Molecule Multivalent Interactions Revealed by Plasmon-Enhanced FluorescenceClick to copy article link

- Research news

Multivalency as an interaction principle is widely utilized in nature. It enables specific and strong binding by multiple weak interactions through enhanced avidity and is a core process in immune recognition and cellular signaling, which is also a current concept in drug design. Here, we use the high signals from plasmon-enhanced fluorescence of nanoparticles to extract binding kinetics and dynamics of multivalent interactions on the single-molecule level and in real time. We study mono-, bi-,…

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Recent publications by network

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Kretsch, R. C., Albrecht, R., Andersen, E. S., Chen, H.-A., Chiu, W., Das, R., Gezelle, J. G., Hartmann, M. D., Höbartner, C., Hu, Y., Jadhav, S., Johnson, P. E., Jones, C. P., Koirala, D., Kristoffersen, E. L., Largy, E., Lewicka, A., Mackereth, C. D., Marcia, M. ... Kryshtafovych, A. (2026). Functional relevance of CASP16 nucleic acid predictions as evaluated by structure providers. Proteins: Structure, Function and Bioinformatics, 94(1), 51-78. https://doi.org/10.1002/prot.70043
Astono, J., Jørgensen, A. G., Bus, C., Nielsen, S. D. H., Kjems, J. & Sundekilde, U. K. (2026). Global protein profiling of human milk using pre-enriched RNA-sequence libraries. Scientific Reports, 16(1), Article 11827. https://doi.org/10.1038/s41598-026-41374-w
Bai, M., Qin, R., Zhang, F., Aranburu, J. Z., Wang, Z., Xu, J., Zhang, X., Dong, M. & Liu, L. (2026). Harnessing smart biointerfaces: From precision tumor cell capture to clinical applications. Sensors and Actuators B: Chemical, 463, Article 140059. https://doi.org/10.1016/j.snb.2026.140059
Chrenková, A., Nashier, P., Madsen, C. L., Singh, M., Nielsen, J., Otzen, D. E., Enghild, J. J., Macek, B., Skjerning, R. B. & Brodersen, D. E. (2026). Homologous HipA-like kinases are controlled by internal translational initiation and genetic organisation. FEBS Letters, 600(3), 356-369. https://doi.org/10.1002/1873-3468.70234
Tvilum, M. S., Nielsen, C. B., Steensgaard, I., Poulsen, T. B., Johannsen, M. & Tørring, T. (2026). Hypoxia-induced production of the cyclolipodepsipeptide BE-43547 by Micromonospora sp. RV43. Microbiology, 172(2), Article 001662. https://doi.org/10.1099/mic.0.001662
Amin, H., Cramer, C., Finster, K., Real, F. G., Gislason, T., Holm, M., Janson, C., Jögi, N. O., Jogi, R., Malinovschi, A., Modig, L., Norbäck, D., Shigdel, R., Sigsgaard, T., Svanes, C., Thorarinsdottir, H., Wouters, I. M., Šantl-Temkiv, T., Schlünssen, V. & Bertelsen, R. J. (2026). Indoor airborne bacterial communities and adult lung health: A cross-sectional study. International Journal of Hygiene and Environmental Health, 274, Article 114780. https://doi.org/10.1016/j.ijheh.2026.114780
Samarth, P., Fedoseev, G., Bulak, M., Ioppolo, S., Hornekær, L., Van Dishoeck, E. F., Linnartz, H. & Chuang, K. J. (2026). In situ characterization of volatile and refractory hydrocarbons produced by UV photolysis of interstellar C 2H 2ice. Astronomy and Astrophysics, 705, Article A229. https://doi.org/10.1051/0004-6361/202556672
Nielsen, K. H. & Ravn, T. (2026). Kunstig intelligens i sundhedsvæsenet: Historiske rødder, teknologiske skift og samfundsmæssige konsekvenser. Bibliotek for Læger, 218(1), 12-21.
Szerlauth, A., Anand, S., Szenti, I., Chen, M., Dong, M., Kónya, Z. & Szilágyi, I. (2026). Layered double hydroxide nanozyme decorated polycaprolactone membranes as superoxide radical scavengers. ChemPhysMater, 5(1), 100-106. https://doi.org/10.1016/j.chphma.2025.10.001
Andreis, L., Bassetti, F. & Hirsch, C. (2026). LDP for the covariance process in fully connected Gaussian neural networks. Electronic Journal of Probability, 31, Article 22. https://doi.org/10.1214/26-EJP1477

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Revised 03.03.2026
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Kalinka Hansen