AUNAB - Aarhus University Network on Artificial Biology

Aarhus University Seal

Publications

Recent research news on Artificial Biology

Receptor-Mediated Transmembrane Activation of Protein Folding in Synthetic Cells

- Research news

An article from the Zelikin lab just published in Bioconjugate Chemistry has been selected as the American Chemical Society Editor´s Choice (the one article chosen each day from the entire ACS portfolio to be highlighted for quality and/or broad interest).

Distinct Network Morphologies from In Situ Polymerization of Microtubules in Giant Polymer-Lipid Hybrid Vesicles

- Research news

Creating artificial cells with a dynamic cytoskeleton, akin to those in living cells, is a major goal in bottom-up synthetic biology. In this study, we demonstrate the in situ polymerization of microtubules encapsulated in giant polymer-lipid hybrid vesicles (GHVs) composed of 1,2-dioleoyl-sn-glycero-3-phosphocholine and an amphiphilic block copolymer. The block copolymer is comprised of poly(cholesteryl methacrylate-co-butyl methacrylate) as the hydrophobic block and either…

Cell Membrane Vesicle Camouflaged Artificial Cells

- Research news

The integration of artificial and mammalian cells into semi-synthetic aggregates remains a challenge in bottom-up synthetic biology. Here, the fabrication of cell membrane vesicles (CMV) from HepG2 cells and their use as a coating for alginate microgels to produce camouflaged artificial cells (ACs) is demonstrated. These ACs are used for the assembly of either synthetic aggregates or semi-synthetic aggregates. In the first case, a predator-defendant and a liver-like synthetic aggregates are…

Researchers propose a roadmap towards the synthesis of life

- Research news

A new perspective article by 57 international researchers, including Associate Professor Ebbe Sloth Andersen, outlines a roadmap for the synthesis of life. The paper explores key traits like resilience, sustainability, and evolution, and how synthetic life could revolutionize biotechnology, medicine, and materials science.

Single-Molecule Multivalent Interactions Revealed by Plasmon-Enhanced FluorescenceClick to copy article link

- Research news

Multivalency as an interaction principle is widely utilized in nature. It enables specific and strong binding by multiple weak interactions through enhanced avidity and is a core process in immune recognition and cellular signaling, which is also a current concept in drug design. Here, we use the high signals from plasmon-enhanced fluorescence of nanoparticles to extract binding kinetics and dynamics of multivalent interactions on the single-molecule level and in real time. We study mono-, bi-,…

Page 2 of 6

Recent publications by network

Sort by: Date | Author | Title

Lin, L., Zhang, H., Cui, H., Xu, M., Cao, S., Zheng, G. & Dong, M. (2013). Preparation and antibacterial activities of hollow silica-Ag spheres. Colloids and Surfaces B: Biointerfaces, 101, 97-100. https://doi.org/10.1016/j.colsurfb.2012.06.001
Cohen, S. I. A., Linse, S., Luheshi, L. M., Hellstrand, E., White, D. A., Rajah, L., Otzen, D., Vendruscolo, M., Dobson, C. M. & Knowles, T. P. J. (2013). Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism. Proceedings of the National Academy of Sciences (PNAS), 110(24), 9758-9763. https://doi.org/10.1073/pnas.1218402110
Gonzalez, B. B., Dagnæs-Hansen, F., Fenton, R. A., Gao, S., Hein, S., Dong, M., Kjems, J. & Howard, K. A. (2013). Protection and systemic translocation of siRNA following oral administration of chitosan/siRNA nanoparticles. Molecular Therapy - Nucleic Acids, 2(1), 1-8. Article e76. https://doi.org/10.1038/mtna.2013.2
Brinkmann, C. R., Thiel, S. & Otzen, D. (2013). Protein:fatty acid complexes: Biochemistry, biophysics and function. FEBS journal, 280(8), 1733–1749. https://doi.org/10.1111/febs.12204
Howard, K. & Peer, D. (2013). Providing the full picture: A mandate for standardizing nanoparticle-based drug delivery. Nanomedicine, 8(7), 1031-1033. https://doi.org/10.2217/NNM.13.95
Pigolotti, S., Lizana, L., Otzen, D. & Sneppen, K. (2013). Quality control system response to stochastic growth of amyloid fibrils. FEBS Letters, 587(9), 1405-1410. https://doi.org/10.1016/j.febslet.2013.03.018
Boote, C., Dooley, E. P., Gardner, S. J., Kamma-Lorger, C. S., Hayes, S., Nielsen, K., Hjortdal, J., Sørensen, T. L.-M., Terrill, N. J. & Meek, K. M. (2013). Quantification of collagen ultrastructure after penetrating keratoplasty - implications for corneal biomechanics. PLoS One, 8(7), e68166. https://doi.org/10.1371/journal.pone.0068166
Lazar, P., Zhang, S., Šafářová, K., Li, Q., Froning, J. P., Granatier, J., Hobza, P., Zbořil, R., Besenbacher, F., Dong, M. & Otyepka, M. (2013). Quantification of the interaction forces between metals and graphene by quantum chemical calculations and dynamic force measurements under ambient conditions. ACS Nano, 7(2), 1646-1651. https://doi.org/10.1021/nn305608a
Nielsen, S. B. & Otzen, D. (2013). Quartz crystal microbalances as tools for probing protein-membrane interactions. In J. Kleinschmidt (Ed.), Lipid-Protein Interactions: Methods and Protocols: Methods in Molecular Biology (Vol. 974, pp. 1-21). https://doi.org/10.1007/978-1-62703-275-9_1
Jensen, P. W., Falconi, M., Kristoffersen, E. L., Simonsen, A. T., Cifuentes, J. B., Marcussen, L., Hougaard, R. F., Vagner, J., Harmsen, C., Jensen, S. J., Ho, Y.-P., Withers, M. A., Lupski, J. R., Koch, J. E., Desideri, A., Knudsen, B. R. & Stougaard, M. (2013). Real-time detection of TDP1 activity using a fluorophore-quencher coupled DNA-biosensor. Biosensors and Bioelectronics, Volume 48, 230–237. https://doi.org/10.1016/j.bios.2013.04.019

Displaying results 2401 to 2410 out of 3494

Previous

237

238

239

240

241

242

243

244

245

246

Next

Revised 03.03.2026
-
Kalinka Hansen