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Recent research news on Artificial Biology

Receptor-Mediated Transmembrane Activation of Protein Folding in Synthetic Cells

- Research news

An article from the Zelikin lab just published in Bioconjugate Chemistry has been selected as the American Chemical Society Editor´s Choice (the one article chosen each day from the entire ACS portfolio to be highlighted for quality and/or broad interest).

Distinct Network Morphologies from In Situ Polymerization of Microtubules in Giant Polymer-Lipid Hybrid Vesicles

- Research news

Creating artificial cells with a dynamic cytoskeleton, akin to those in living cells, is a major goal in bottom-up synthetic biology. In this study, we demonstrate the in situ polymerization of microtubules encapsulated in giant polymer-lipid hybrid vesicles (GHVs) composed of 1,2-dioleoyl-sn-glycero-3-phosphocholine and an amphiphilic block copolymer. The block copolymer is comprised of poly(cholesteryl methacrylate-co-butyl methacrylate) as the hydrophobic block and either…

Cell Membrane Vesicle Camouflaged Artificial Cells

- Research news

The integration of artificial and mammalian cells into semi-synthetic aggregates remains a challenge in bottom-up synthetic biology. Here, the fabrication of cell membrane vesicles (CMV) from HepG2 cells and their use as a coating for alginate microgels to produce camouflaged artificial cells (ACs) is demonstrated. These ACs are used for the assembly of either synthetic aggregates or semi-synthetic aggregates. In the first case, a predator-defendant and a liver-like synthetic aggregates are…

Researchers propose a roadmap towards the synthesis of life

- Research news

A new perspective article by 57 international researchers, including Associate Professor Ebbe Sloth Andersen, outlines a roadmap for the synthesis of life. The paper explores key traits like resilience, sustainability, and evolution, and how synthetic life could revolutionize biotechnology, medicine, and materials science.

Single-Molecule Multivalent Interactions Revealed by Plasmon-Enhanced FluorescenceClick to copy article link

- Research news

Multivalency as an interaction principle is widely utilized in nature. It enables specific and strong binding by multiple weak interactions through enhanced avidity and is a core process in immune recognition and cellular signaling, which is also a current concept in drug design. Here, we use the high signals from plasmon-enhanced fluorescence of nanoparticles to extract binding kinetics and dynamics of multivalent interactions on the single-molecule level and in real time. We study mono-, bi-,…

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Recent publications by network

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Hirsch, C. & Owada, T. (2026). Limit theorems under heavy-tailed scenario in the age-dependent random connection models. Stochastic Processes and Their Applications, 192, Article 104815. https://doi.org/10.1016/j.spa.2025.104815
Neis, K., Civit Pitarch, L., Pedersen, K., Schachtner, M., Wengel, J., Wagner, R., Thiel, S., Kjems, J. & Valero Moreno, J. (2026). Lock, Protect, and Bind: In Vitro Selection of Locked Nucleic Acid-Modified Aptamers Using a Mutant T7 RNA Polymerase. Small Structures, 7(3), Article e202500677. https://doi.org/10.1002/sstr.202500677
Li, B., Dong, M. & Li, Q. (2026). Macroscale superlubricity under high pressure enabled by partially oxidized MXene nanosheets. Materials Today Nano, 33, Article 100748. https://doi.org/10.1016/j.mtnano.2025.100748
Wang, A. G., Wu, W. M., Dong, M. D., Ji, M., Yu, Z. Q., Liang, Y. X. & Xu, M. Y. (2026). Making waves: Harnessing electroactive microorganisms for efficient and sustainable removal of emerging contaminants in wastewater treatment plants. Water Research, 289, Article 124900. https://doi.org/10.1016/j.watres.2025.124900
Nielsen, K. H. (2026). Markovnikovs regel. Weekendavisen, Sektion 4 (Ideer), 5.
Adam, L., Molenkamp, W. H., Nowak, J. S., Farzadfard, A., Gaarthuis, K., Kumar, R., Nielsen, J., Otzen, D. E., Johansson, J. & Abelein, A. (2026). Mechanism-selective inhibition of α-synuclein aggregation by the chaperone-like BRICHOS domain. The Journal of Biological Chemistry, 302(6), 113117. Article 113117. https://doi.org/10.1016/j.jbc.2026.113117
Hoetzel, J., Walbrun, A., Schäfer, M., Wang, T., Jørgensen, A. G., Becker, O., Stamatakis, K., Gunawan, V., Reichardt, L., Boettger, L., Bruckhoff, R. W., Kjems, J., Wachtveitl, J., Rief, M. & Suess, B. (2026). Mechanism underlying the high regulatory performance of the doxycycline riboswitch G12. Nature Communications, 17(1). https://doi.org/10.1038/s41467-026-76256-2
Zhang, Y., Zhao, F., Chen, S., Li, B., Dong, J., Chen, Y., Liu, Y., Qiao, A. & Chen, M. (2026). Melt electrowriting-enabled hybrid platforms: Toward functional biomimetic scaffolds for cellular interaction and tissue regeneration. Acta Biomaterialia, 213, 21-61. https://doi.org/10.1016/j.actbio.2026.02.015
Nielsen, K. H. (2026). Menneskets tidsalder. Weekendavisen, Sektion 4 (Ideer), 5.
Kromm, F. E. H., Møller, S. L. B., Jensen, A. S., Wørmer, G. J., Rasmussen, M. H., B. Svenningsen, E., Tørring, T. & Poulsen, T. B. (2026). Modular Total Synthesis of Lasalocid Acid A through Direct C(sp3)–C(sp3) Attached Ring Construction. Journal of the American Chemical Society, 148(1), 249-257. https://doi.org/10.1021/jacs.5c11543

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Revised 03.03.2026
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Kalinka Hansen