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AUNAB - Aarhus University Network on Artificial Biology

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Recent research news on Artificial Biology

27 November 2023 - Research news

In this work, synthetic cells equipped with an artificial signaling pathway that connects an extracellular trigger event to the activation of intracellular transcription are engineered. Learning from nature, this is done via an engineering of responsive enzymes, such that activation of enzymatic activity can be triggered by an external biochemical stimulus. Reversibly deactivated creatine kinase to achieve triggered production of adenosine triphosphate, and a reversibly deactivated nucleic acid…

01 May 2023 - Research news

Nanopores are label-free single-molecule analytical tools that show great potential for stochastic sensing of proteins. Here, we described a ClyA nanopore functionalized with different nanobodies through a 5–6 nm DNA linker at its periphery. Ty1, 2Rs15d, 2Rb17c, and nb22 nanobodies were employed to specifically recognize the large protein SARS-CoV-2 Spike, a medium-sized HER2 receptor, and the small protein murine urokinase-type plasminogen activator (muPA), respectively. The pores modified with…

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Recent publications by network

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Nielsen, L. T., Vase, K. H., Dong, M., Besenbacher, F., Pedersen, S. U. & Daasbjerg, K. (2007). Electrochemical Approach for Constructing a Monolayer of Thiophenolates from Grafted Multilayers of Diaryl Disulfides. Abstract from 3^rdECHEMS Meeting: Electrochemistry in "Nanosystems and Molecules at Work", Trest Castle, Czech Republic.

Nielsen, L. T., Vase, K. H., Dong, M., Besenbacher, F., Pedersen, S. U. & Daasbjerg, K. (2007). Electrochemical Approach for Constructing a Monolayer of Thiophenolates from Grafted Multilayers of Diaryl Disulfides. Journal of the American Chemical Society, 129(7), 1888-1889. https://doi.org/10.1021/ja0682430

Ebbesen, M. & Pedersen, B. D. (2007). Empirical Investigation of the Ethical Reasoning of Physicians and Molecular Biologists - the Importance of the Four Principles of Biomedical Ethics. Philosophy, Ethics, and Humanities in Medicine, (2).

Xu, W., Dong, M., Vázquez-Campos, S., Gersen, H., Laegsgaard, E., Stensgaard, I., Crego-Calama, M., Reinhoudt, D. N., Linderoth, T. R. & Besenbacher, F. (2007). Enhanced stability of large molecules vacuum-sublimated onto Au(111) achieved by incorporation of coordinated Au-atoms. Journal of the American Chemical Society, 129(35), 10624-5. https://doi.org/10.1021/ja0725448

Mailund, T., Pedersen, C. N. S., Bardino, J., Vinter, B. & Karlsen, H. (2007). Experiences with GeneRecon on MiG. Future Generation Computer Systems - The International Journal of eScience, 23, 580-586. https://doi.org/10.1016/j.future.2006.09.003

Nielsen, K. H. (2007). Folkekrav. Flere hjerner i spalterne, tak. Politiken, 10.

Malmos, K., Dong, M., Besenbacher, F., Daasbjerg, K. & Pedersen, S. U. (2007). Formation with the use of Electrostatic Repulsion of Covalent Attached Thin Layer on Glassy Carbon Surface. Paper presented at Electrochemical Science and Technology, Aarhus, Denmark.

Nielsen, K. H. (2007). Forskning, formidling og forvirring. Humaniora, (3).

Nielsen, K. H. (2007). Første blik: Om Gerhard Richters editioner med særligt fokus på Erster Blick (2000). Billedkunst. Kritisk-videnskabeligt tidsskrift, 15(1), 30-36.

Braren, I., Blank, S., Seismann, H., Deckers, S., Ollert, M., Grunwald, T. & Spillner, E. (2007). Generation of human monoclonal allergen-specific IgE and IgG antibodies from synthetic antibody libraries. Clinical Chemistry, 53(5), 837-44. https://doi.org/10.1373/clinchem.2006.078360

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Kalinka Hansen