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Recent research news on Artificial Biology

27 November 2023 - Research news

In this work, synthetic cells equipped with an artificial signaling pathway that connects an extracellular trigger event to the activation of intracellular transcription are engineered. Learning from nature, this is done via an engineering of responsive enzymes, such that activation of enzymatic activity can be triggered by an external biochemical stimulus. Reversibly deactivated creatine kinase to achieve triggered production of adenosine triphosphate, and a reversibly deactivated nucleic acid…

01 May 2023 - Research news

Nanopores are label-free single-molecule analytical tools that show great potential for stochastic sensing of proteins. Here, we described a ClyA nanopore functionalized with different nanobodies through a 5–6 nm DNA linker at its periphery. Ty1, 2Rs15d, 2Rb17c, and nb22 nanobodies were employed to specifically recognize the large protein SARS-CoV-2 Spike, a medium-sized HER2 receptor, and the small protein murine urokinase-type plasminogen activator (muPA), respectively. The pores modified with…

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Nielsen, K. H. (2006). 100 års videnskabsformidling. In R. S. Kjærgaard (Ed.), Elfenbenstårnet: Universiteter mellem forskning og formidling (pp. 35-54). Aarhus Universitetsforlag.

Dong, MD., Hovgaard, M. B., Xu, S., Otzen, D. E. & Besenbacher, F. (2006). AFM study of glucagon fibrillation via oligomeric structures resulting in interwoven fibrils. Nanotechnology, (17), 4003-4009.

Ebbesen, M. (2006). A Journey into the World of Atoms and Molecules. Journal of Lutheran Ethics, (2).

Jonstrup, S. P., Koch, J. & Kjems, J. (2006). A microRNA detection system based on padlock probes and rolling circle amplification. RNA, 12(9), 1747-1752. https://doi.org/10.1261/rna.110706

Nielsen, K. H. (2006). Anmeldelse af: Claus Holm: Forståelsens rasen (2005).

Nielsen, K. H. (2006). Anmeldelse af: David Finer, Fokus Forskning (2005).

Nielsen, K. H. (2006). Anmeldelse af: Jesper Gulddal, red., Pas: identitet, kultur og grænser (2004). Nord Nytt, (98), 119.

Nielsen, K. H. (2006). Anmeldelse af: Ludwig Wittgenstein, Den ukjente dagboken (2004). Nord Nytt, (98), 109.

Lützelberger, M., Reinert, L. S., Das, A. T., Berkhout, B. & Kjems, J. (2006). A novel splice donor site in the gag-pol gene is required for HIV-1 RNA stability. Journal of Biological Chemistry, 281(27), 18644-18651. https://doi.org/10.1074/jbc.M513698200

Lomstein, B. A., Guldberg, L. B., Neubauer, A. T. A., Hansen, J., Donnelly, A., Herbert, R. A., Viaroli, P., Giordani, G., Azzoni, R., de Wit, R. & Finster, K. (2006). Benthic decomposition of Ulva lactuca: A controlled laboratory experiment. Aquatic Botany, 85(4), 271-281. https://doi.org/10.1016/j.aquabot.2006.05.006

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