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AUNAB - Aarhus University Network on Artificial Biology

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Recent research news on Artificial Biology

27 November 2023 - Research news

In this work, synthetic cells equipped with an artificial signaling pathway that connects an extracellular trigger event to the activation of intracellular transcription are engineered. Learning from nature, this is done via an engineering of responsive enzymes, such that activation of enzymatic activity can be triggered by an external biochemical stimulus. Reversibly deactivated creatine kinase to achieve triggered production of adenosine triphosphate, and a reversibly deactivated nucleic acid…

01 May 2023 - Research news

Nanopores are label-free single-molecule analytical tools that show great potential for stochastic sensing of proteins. Here, we described a ClyA nanopore functionalized with different nanobodies through a 5–6 nm DNA linker at its periphery. Ty1, 2Rs15d, 2Rb17c, and nb22 nanobodies were employed to specifically recognize the large protein SARS-CoV-2 Spike, a medium-sized HER2 receptor, and the small protein murine urokinase-type plasminogen activator (muPA), respectively. The pores modified with…

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Recent publications by network

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Nielsen, K. H. (2018). Fodbold. Weekendavisen, Sektion 4 (Ideer), 10.

Aliakbari, F., Shabani, A. A., Bardania, H., Mohammad-Beigi, H., Tayaranian Marvian, A., Dehghani Esmatabad, F., Vafaei, A. A., Shojaosadati, S. A., Saboury, A. A., Christiansen, G., Otzen, D. E. & Morshedi, D. (2018). Formulation and anti-neurotoxic activity of baicalein-incorporating neutral nanoliposome. Colloids and surfaces. B, Biointerfaces, 161, 578-587. https://doi.org/10.1016/j.colsurfb.2017.11.023

Nielsen, K. H. (2018). Forskningen bliver bedre, hvis der er plads til held og tilfældigheder. Videnskab.dk. https://videnskab.dk/kultur-samfund/forskningen-bliver-bedre-hvis-der-er-plads-til-held-og-tilfaeldigheder

Nielsen, K. H. (2018). ‘For the nation as a whole and for each individual in it’: The Royal Society’s public understanding of science report (1985) in historical context. Abstract from European Society for the History of Science, London, United Kingdom.

Nielsen, K. H. (2018). Frankenstein. Weekendavisen, 10.

Nielsen, K. H. (2018). Fra rigmands-eventyr til krig: Oliens historie er en sortplettet affære. Videnskab.dk. https://videnskab.dk/teknologi-innovation/fra-rigmands-eventyr-til-krig-oliens-historie-er-en-sortplettet-affaere

Zając, S., Geary, C., Andersen, E. S., Dabrowski-Tumanski, P., Sulkowska, J. I. & Sułkowski, P. (2018). Genus trace reveals the topological complexity and domain structure of biomolecules. Scientific Reports, 8(1), Article 17537. https://doi.org/10.1038/s41598-018-35557-3

Zhu, C., Li, Q., Dong, M. & Han, X. (2018). Giant Unilamellar Vesicle Microarrays for Cell Function Study. Analytical Chemistry, 90(24), 14363-14367. https://doi.org/10.1021/acs.analchem.8b03825

Chang, C. C., Venø, M. T., Chen, L., Ditzel, N., Le, D. Q. S., Dillschneider, P., Kassem, M. & Kjems, J. (2018). Global MicroRNA Profiling in Human Bone Marrow Skeletal—Stromal or Mesenchymal–Stem Cells Identified Candidates for Bone Regeneration. Molecular Therapy, 26(2), 593-605. https://doi.org/10.1016/j.ymthe.2017.11.018

Nielsen, K. H. (2018). Hacker. Weekendavisen, Sektion 4 (Ideer), 10.

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Kalinka Hansen