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AUNAB - Aarhus University Network on Artificial Biology

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Recent research news on Artificial Biology

27 November 2023 - Research news

In this work, synthetic cells equipped with an artificial signaling pathway that connects an extracellular trigger event to the activation of intracellular transcription are engineered. Learning from nature, this is done via an engineering of responsive enzymes, such that activation of enzymatic activity can be triggered by an external biochemical stimulus. Reversibly deactivated creatine kinase to achieve triggered production of adenosine triphosphate, and a reversibly deactivated nucleic acid…

01 May 2023 - Research news

Nanopores are label-free single-molecule analytical tools that show great potential for stochastic sensing of proteins. Here, we described a ClyA nanopore functionalized with different nanobodies through a 5–6 nm DNA linker at its periphery. Ty1, 2Rs15d, 2Rb17c, and nb22 nanobodies were employed to specifically recognize the large protein SARS-CoV-2 Spike, a medium-sized HER2 receptor, and the small protein murine urokinase-type plasminogen activator (muPA), respectively. The pores modified with…

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Recent publications by network

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Kragh, H. & Nielsen, K. H. (Eds.) (2015). 50 opfindelser: Højdepunkter i teknologien. Aarhus Universitetsforlag.

Goddiksen, M. P. & Nielsen, K. H. (2015). A Blended Learning Approach to Philosophy of Science. Poster session presented at Teaching philosophy of science to science students, Aarhus, Denmark.

Ebbesen, M., Andersen, S. & Pedersen, F. S. (2015). A conceptual framework for the ethics of synthetic biology. Akademisk Kvarter, 12, 203-223.

Nielsen, K. H. (2015). A Curious Story: How Curious George was Adapted for Entertainment Media and Science Education. Abstract from Stories about science, Manchester, United Kingdom. http://thescienceandentertainmentlab.com/wp-content/uploads/2014/09/SAS_Programme_May2015.pdf

Li, R., Peréz, B., Jian, H., Gao, R., Dong, MD. & Guo, Z. (2015). Acyl-peptide releasing enzyme from Sulfolobus tokodaii (ST0779) as a novel promiscuous biocatalyst for aldol addition. Catalysis Communications, 66, 111-115. https://doi.org/10.1016/j.catcom.2015.03.030

Dappe, Y. J., Andersen, M., Balog, R., Hornekær, L. & Bouju, X. (2015). Adsorption and STM imaging of polycyclic aromatic hydrocarbons on graphene. Physical Review B, 91(4), Article 045427. https://doi.org/10.1103/PhysRevB.91.045427

Cao, Y., Tao, L., Wang, J., Aslan, H., Liu, L. & Dong, MD. (2015). AFM study on amyloid peptide - graphene oxide assembly and its interaction with liposome. Journal of Self-Assembly and Molecular Electronics, 3, 11-16. Article 2. http://riverpublishers.com/journal_article.php?j=JSAME/3/1/2

Hirsch, C. (2015). A Harris-Kesten theorem for confetti percolation. Random Structures Algorithms, 47(2), 361-385.

Howard, K. A. (2015). Albumin: The next-generation delivery technology. Therapeutic Delivery, 6(3), 265-268. https://doi.org/10.4155/tde.14.124

Košmrlj, A., Cordsen, P., Kyrsting, A., Otzen, D., Oddershede, L. B. & Jensen, M. H. (2015). A monomer-trimer model supports intermittent glucagon fibril growth. Scientific Reports, 5, 1-6. Article 9005. https://doi.org/10.1038/srep09005

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Kalinka Hansen