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Recent research news on Artificial Biology

27 November 2023 - Research news

In this work, synthetic cells equipped with an artificial signaling pathway that connects an extracellular trigger event to the activation of intracellular transcription are engineered. Learning from nature, this is done via an engineering of responsive enzymes, such that activation of enzymatic activity can be triggered by an external biochemical stimulus. Reversibly deactivated creatine kinase to achieve triggered production of adenosine triphosphate, and a reversibly deactivated nucleic acid…

01 May 2023 - Research news

Nanopores are label-free single-molecule analytical tools that show great potential for stochastic sensing of proteins. Here, we described a ClyA nanopore functionalized with different nanobodies through a 5–6 nm DNA linker at its periphery. Ty1, 2Rs15d, 2Rb17c, and nb22 nanobodies were employed to specifically recognize the large protein SARS-CoV-2 Spike, a medium-sized HER2 receptor, and the small protein murine urokinase-type plasminogen activator (muPA), respectively. The pores modified with…

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Andersen, E. S., Rosenblad, M. A., Larsen, N., Westergaard, J. C., Burks, J., Wower, I. K., Wower, J., Gorodkin, J., Samuelsson, T. & Zwieb, C. (2006). The tmRDB and SRPDB resources. Nucleic Acids Res. , 34(Database issue), D163-8.

Kolln, J., Ren, H.-M., Da, R.-R., Zhang, Y., Spillner, E., Olek, M., Hermanowicz, N., Hilgenberg, L. G., Smith, M. A., van den Noort, S. & Qin, Y. (2006). Triosephosphate isomerase- and glyceraldehyde-3-phosphate dehydrogenase-reactive autoantibodies in the cerebrospinal fluid of patients with multiple sclerosis. Journal of Immunology, 177(8), 5652-8.

Nielsen, H., Nielsen, K. H. & Thomsen, M. L. (2006). Videnproduktion som komplekst socialt system. In H. Nielsen & K. H. Nielsen (Eds.), Viden uden grænser 1920-1970: Dansk Naturvidenskabs Historie (Vol. 4, pp. 25-37). Aarhus Universitetsforlag.

Nielsen, K. H. & Nielsen, H. (2006). Videnskaben på barrikaderne. Information, 18-9.

Nielsen, K. H. (2006). Videnskaben viser flaget: Galathea 1- og 2-ekspeditionerne. In N. Kousdal (Ed.), Københavns Universitets Almanak 2007 (pp. 108-117)

Nielsen, K. H. (2006). Videnskab, stat og medier: Galathea 2 (1950-52) som postkolonial forsknings- og formidlingsekspedition.

Nielsen, H. & Nielsen, K. H. (Eds.) (2006). Viden uden grænser - Dansk Naturvidenskabs Historie 4, 1920-1970. Aarhus Universitetsforlag.

Brunak, S. & Andersen, E. S. (2006). Virtuelle immunsystemer. Aktuel Naturvidenskab, (1), 20-23.

Andersen, E. S. & Kjems, J. (2006). Virus er naturens selviske nanorobotter. In A.-L. S. Petersen & F. Besenbacher (Eds.), Nanoteknologi: 12 historier om den nyeste danske forskning (pp. 42-45).

Ebbesen, M. (2006). What Can Nanotechnology Learn from the Ethical and Societal Implications of Biotechnology? Forum TTN, (15), 32-50.

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