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AUNAB - Aarhus University Network on Artificial Biology

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Recent research news on Artificial Biology

27 November 2023 - Research news

In this work, synthetic cells equipped with an artificial signaling pathway that connects an extracellular trigger event to the activation of intracellular transcription are engineered. Learning from nature, this is done via an engineering of responsive enzymes, such that activation of enzymatic activity can be triggered by an external biochemical stimulus. Reversibly deactivated creatine kinase to achieve triggered production of adenosine triphosphate, and a reversibly deactivated nucleic acid…

01 May 2023 - Research news

Nanopores are label-free single-molecule analytical tools that show great potential for stochastic sensing of proteins. Here, we described a ClyA nanopore functionalized with different nanobodies through a 5–6 nm DNA linker at its periphery. Ty1, 2Rs15d, 2Rb17c, and nb22 nanobodies were employed to specifically recognize the large protein SARS-CoV-2 Spike, a medium-sized HER2 receptor, and the small protein murine urokinase-type plasminogen activator (muPA), respectively. The pores modified with…

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Recent publications by network

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Drewsen, M., Bowe, P. D., Hornekær, L., Brodersen, C., Schiffer, J. P. & Hangst, J. S. (1999). Sympathetic cooling and crystallization of ions in a linear Paul trap. In H. E. Daniel, D. H. E. Dubin & D. Schneider (Eds.), AIP (pp. 305)

Bowe, P. D., Hornekær, L., Brodersen, C., Drewsen, M. & Hangst, J. S. (1999). Sympathetic crystallization of trapped ions. Physical Review Letters, 82, 2071.

Blaaberg, V., Mouritsen, K. N. & Finster, K. (1998). Diel cycles of sulphate reduction in sediments of a Zostera marina-bed. Aquatic Microbial Ecology, 15, 97-102.

Finster, K., Liesack, W. & Thamdrup, B. (1998). Elemental sulfur and thiosulfate disproportionation by Desulfocapsa sulfoexigens sp. nov., a new anaerobic bacterium isolated from marine surface sediment. Applied and Environmental Microbiology, 64(1), 119-25.

Christophersen, C., Otzen, D. E., Norman, B. E., Christensen, S. & Schäfer, T. (1998). Enzymatic characterisation of novamyl®, a thermostable α-amylase. Starch/Staerke, 50(1), 39-45. https://doi.org/10.1002/(SICI)1521-379X(199801)50:1<39::AID-STAR39>3.0.CO;2-S

Hornekær, L., Drewsen, M., Brodersen, C., Schiffer, J. P. & Hangst, J. S. (1998). Ion crystals in a linear Paul trap. Hyperfine Interactions, 115, 37-40.

Drewsen, M., Brodersen, C., Hornekær, L., Hangst, J. S. & Schiffer, J. P. (1998). Large ion crystals in a linear paul trap. Physical Review Letters, 81(14), 2878-2881.

Damgaard, C. K., Dyhr-Mikkelsen, H. & Kjems, J. (1998). Mapping the RNA binding sites for human immunodeficiency virus type-1 gag and NC proteins within the complete HIV-1 and -2 untranslated leader regions. Nucleic Acid Research, 26(16).

Nielsen, K. H. (1998). Richard L. Hills, Power from Wind. A History of Windmill Technology. Cambridge etc. (Cambridge University Press) 1996. Centaurus (Copenhagen), 40, 398-399.

Blaabjerg, V. & Finster, K. (1998). Sulphate reduction associated with roots and rhizomes of the marine macrophyte Zostera marina. Aquatic Microbial Ecology, 15(3), 311-314. https://doi.org/10.3354/ame015311

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Kalinka Hansen