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Recent research news on Artificial Biology

27 November 2023 - Research news

In this work, synthetic cells equipped with an artificial signaling pathway that connects an extracellular trigger event to the activation of intracellular transcription are engineered. Learning from nature, this is done via an engineering of responsive enzymes, such that activation of enzymatic activity can be triggered by an external biochemical stimulus. Reversibly deactivated creatine kinase to achieve triggered production of adenosine triphosphate, and a reversibly deactivated nucleic acid…

01 May 2023 - Research news

Nanopores are label-free single-molecule analytical tools that show great potential for stochastic sensing of proteins. Here, we described a ClyA nanopore functionalized with different nanobodies through a 5–6 nm DNA linker at its periphery. Ty1, 2Rs15d, 2Rb17c, and nb22 nanobodies were employed to specifically recognize the large protein SARS-CoV-2 Spike, a medium-sized HER2 receptor, and the small protein murine urokinase-type plasminogen activator (muPA), respectively. The pores modified with…

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Madsen, N., Bowe, P. D., Drewsen, M., Hornekær, L., Kjærgaard, N., Labrador, A., Nielsen, J. S., Schiffer, J. P., Shi, P. & Hangst, J. S. (1999). Density limitations in a stored laser-cooled ion beam. Physical Review Letters, 83, 4301.

Nielsen, K. H. (1999). Interpreting Wind Power vs. the Electric Power System: A Danish Case Study. Centaurus (Copenhagen), 41(1-2), 161-177.

Nielsen, K. H. (1999). Norm og netværk: En Latour'sk analyse af Norm for last og sikkerhed for vindmøllekonstruktioner, DS 472. Videnskabsforskning, (24), 2-18.

Askjær, P., Bachi, A., Wilm, M., Bischoff, R., Weeks, D., Ohno, M., Kjems, J., Mattaj, I. & Fornerod, M. (1999). RanGTP-regulated interactions of CRM1 with nucleoporins and a shuttling DEAD-box helicase. Molecular and Cellular Biology, 19, 6276-6285.

Nielsen, K. H. (1999). Some Comments on the History of Technology: An Interview with John M. Staudenmaier, SJ. Polhem, 17(2-4), 211-216.

Drewsen, M., Bowe, P. D., Hornekær, L., Brodersen, C., Schiffer, J. P. & Hangst, J. S. (1999). Sympathetic cooling and crystallization of ions in a linear Paul trap. In H. E. Daniel, D. H. E. Dubin & D. Schneider (Eds.), AIP (pp. 305)

Bowe, P. D., Hornekær, L., Brodersen, C., Drewsen, M. & Hangst, J. S. (1999). Sympathetic crystallization of trapped ions. Physical Review Letters, 82, 2071.

Blaaberg, V., Mouritsen, K. N. & Finster, K. (1998). Diel cycles of sulphate reduction in sediments of a Zostera marina-bed. Aquatic Microbial Ecology, 15, 97-102.

Finster, K., Liesack, W. & Thamdrup, B. (1998). Elemental sulfur and thiosulfate disproportionation by Desulfocapsa sulfoexigens sp. nov., a new anaerobic bacterium isolated from marine surface sediment. Applied and Environmental Microbiology, 64(1), 119-25.

Christophersen, C., Otzen, D. E., Norman, B. E., Christensen, S. & Schäfer, T. (1998). Enzymatic characterisation of novamyl®, a thermostable α-amylase. Starch/Staerke, 50(1), 39-45. https://doi.org/10.1002/(SICI)1521-379X(199801)50:1<39::AID-STAR39>3.0.CO;2-S

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