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AUNAB - Aarhus University Network on Artificial Biology

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Recent research news on Artificial Biology

27 November 2023 - Research news

In this work, synthetic cells equipped with an artificial signaling pathway that connects an extracellular trigger event to the activation of intracellular transcription are engineered. Learning from nature, this is done via an engineering of responsive enzymes, such that activation of enzymatic activity can be triggered by an external biochemical stimulus. Reversibly deactivated creatine kinase to achieve triggered production of adenosine triphosphate, and a reversibly deactivated nucleic acid…

01 May 2023 - Research news

Nanopores are label-free single-molecule analytical tools that show great potential for stochastic sensing of proteins. Here, we described a ClyA nanopore functionalized with different nanobodies through a 5–6 nm DNA linker at its periphery. Ty1, 2Rs15d, 2Rb17c, and nb22 nanobodies were employed to specifically recognize the large protein SARS-CoV-2 Spike, a medium-sized HER2 receptor, and the small protein murine urokinase-type plasminogen activator (muPA), respectively. The pores modified with…

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Nielsen, K. H., Nielsen, K. & Heymann, M. (2014). Molekylærmedicinens videnskabsteori og etik. Poster session presented at 1st Annual Meeting of the Danish Network in Philosophy of Science, Odense, Denmark.

Thomsen, T. B., Li, L. & Howard, K. (2014). Mucus barrier-triggered disassembly of siRNA nanocarriers. Nanoscale, 6(21), 12547-54. https://doi.org/10.1039/c4nr01584c

Lü, J., Yang, J., Dong, MD. & Sahin, O. (2014). Nanomechanical spectroscopy of synthetic and biological membranes. Nanoscale, 6(13), 7604-7608. https://doi.org/10.1039/c3nr02643d

Nørby, P., Overgaard, J., Sigaard Christensen, P., Richter, B., Song, X., Dong, MD., Han, A., Skibsted, J., Iversen, B. B. & Johnsen, S. (2014). (NH₄)₄Sn₂S₆·3H ₂O: Crystal structure, thermal decomposition, and precursor for textured thin film. Chemistry of Materials, 26(15), 4494-4504. https://doi.org/10.1021/cm501681r

Kjems, J., Ferapontova, E. & Gothelf, K. V. (Eds.) (2014). Nucleic Acid Nanotechnology. Springer. Nucleic Acids and Molecular Biology Vol. 29 https://doi.org/10.1007/978-3-642-38815-6

Kang, R., Luo, Y., Zou, L., Xie, L., Lysdahl, H., Jiang, X., Chen, C., Bolund, L., Chen, M., Besenbacher, F. & Bunger, C. E. (2014). Oesteogenesis of Human Induced Pluripotent Stem Cells Derived Mesenchymal Stem Cells on hydroxyapatite contained Nanofibers. R S C Advances, 4(11), 5734-5739. https://doi.org/10.1039/C3RA44181D

Lorenzen, N. & Otzen, D. (2014). Oligomers of α-synuclein: picking the culprit in the line-up. Essays in Biochemistry, 56(1), 137-148. https://doi.org/10.1042/bse0560137

Meng, X., Mi, J., Li, Q., Bortolini, C. & Dong, MD. (2014). One dimensional Ba _xSr₁ − _xEr _y Fe₁₂ − _yO₁₉ fibers with magnetic crystalline nanoparticles. Materials Research Express, 1(3), Article 36106. https://doi.org/10.1088/2053-1591/1/3/036106

Gonzalez, B. B., Ebbesen, M. F. & Howard, K. (2014). Polycation-based nanoparticles for RNAi-mediated cancer treatment. Cancer Letters, 352, 66-80. https://doi.org/10.1016/j.canlet.2013.09.023

Skov, A. L., Thrower, J. D. & Hornekær, L. (2014). Polycyclic aromatic hydrocarbons-catalysts for molecular hydrogen formation. Faraday Discussions, 168, 223-234. https://doi.org/10.1039/c3fd00151b

Displaying results 2181 to 2190 out of 3464

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Kalinka Hansen