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AUNAB - Aarhus University Network on Artificial Biology

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Recent research news on Artificial Biology

27 November 2023 - Research news

In this work, synthetic cells equipped with an artificial signaling pathway that connects an extracellular trigger event to the activation of intracellular transcription are engineered. Learning from nature, this is done via an engineering of responsive enzymes, such that activation of enzymatic activity can be triggered by an external biochemical stimulus. Reversibly deactivated creatine kinase to achieve triggered production of adenosine triphosphate, and a reversibly deactivated nucleic acid…

01 May 2023 - Research news

Nanopores are label-free single-molecule analytical tools that show great potential for stochastic sensing of proteins. Here, we described a ClyA nanopore functionalized with different nanobodies through a 5–6 nm DNA linker at its periphery. Ty1, 2Rs15d, 2Rb17c, and nb22 nanobodies were employed to specifically recognize the large protein SARS-CoV-2 Spike, a medium-sized HER2 receptor, and the small protein murine urokinase-type plasminogen activator (muPA), respectively. The pores modified with…

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Mateos-Rivera, A., Øvreås, L., Wilson, B., Yde, J. C. & Finster, K. W. (2018). Activity and diversity of methane-oxidizing bacteria along a Norwegian sub-Arctic glacier forefield. FEMS Microbiology Ecology, 94(5), 1-11. Article fiy059. https://doi.org/10.1093/femsec/fiy059

Zheng, N., He, J., Gao, J., Huang, Y., Besenbacher, F. & Dong, M. (2018). Adhesion force measured by atomic force microscopy for direct carbon fiber-epoxy interfacial characterization. Materials and Design, 145, 218-225. https://doi.org/10.1016/j.matdes.2018.02.060

Santl-Temkiv, T., Gosewinkel, U., Starnawski, P., Lever, M. & Finster, K. (2018). Aeolian dispersal of bacteria in southwest Greenland: their sources, abundance, diversity and physiological states. FEMS Microbiology Ecology, 94(4), Article fiy031. https://doi.org/10.1093/femsec/fiy031

Fazekas-Singer, J., Singer, J., Ilieva, K. M., Matz, M., Herrmann, I., Spillner, E., Karagiannis, S. N. & Jensen-Jarolim, E. (2018). AllergoOncology: Generating a canine anti-cancer IgE against the epidermal growth factor receptor. Journal of Allergy and Clinical Immunology, 142(3), 973-976.e11. https://doi.org/10.1016/j.jaci.2018.04.021

Knudsen, C. H., ásgrímsdóttir, E. S., Rahimi, K., Gill, K. P., Frandsen, S., Buchholdt, S. H., Chen, M., Kjems, J., Febbraro, F. & Denham, M. (2018). A modified monomeric red fluorescent protein reporter for assessing CRISPR activity. Frontiers in Cell and Developmental Biology, 6(MAY), Article 54. https://doi.org/10.3389/fcell.2018.00054

Huo, P., Zhao, P., Wang, Y., Liu, B. & Dong, MD. (2018). An effective utilization of solar energy: Enhanced photodegradation efficiency of TiO₂/graphene-based composite. Energies, 11(3), 630-649. Article 630. https://doi.org/10.3390/en11030630

Jiang, H., Wang, Z., Yang, Q., Hanif, M., Wang, Z., Dong, L. & Dong, M. (2018). A novel MnO₂/Ti₃C₂Tx MXene nanocomposite as high performance electrode materials for flexible supercapacitors. Electrochimica Acta, 290, 695-703. https://doi.org/10.1016/j.electacta.2018.08.096

Nielsen, C. K., Subbiahdoss, G., Zeng, G., Salmi, Z., Kjems, J., Mygind, T., Snabe, T. & Meyer, R. L. (2018). Antibacterial isoeugenol coating on stainless steel and polyethylene surfaces prevents biofilm growth. Journal of Applied Microbiology, 124(1), 179-187. https://doi.org/10.1111/jam.13634

Huo, P., Zhao, P., Wang, Y., Liu, B., Yin, G. & Dong, MD. (2018). A roadmap for achieving sustainable energy conversion and storage: Graphene-based composites used both as an electrocatalyst for oxygen reduction reactions and an electrode material for a supercapacitor. Energies, 11(1), 167-189. Article 167. https://doi.org/10.3390/en11010167

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Kalinka Hansen