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Recent research news on Artificial Biology

27 November 2023 - Research news

In this work, synthetic cells equipped with an artificial signaling pathway that connects an extracellular trigger event to the activation of intracellular transcription are engineered. Learning from nature, this is done via an engineering of responsive enzymes, such that activation of enzymatic activity can be triggered by an external biochemical stimulus. Reversibly deactivated creatine kinase to achieve triggered production of adenosine triphosphate, and a reversibly deactivated nucleic acid…

01 May 2023 - Research news

Nanopores are label-free single-molecule analytical tools that show great potential for stochastic sensing of proteins. Here, we described a ClyA nanopore functionalized with different nanobodies through a 5–6 nm DNA linker at its periphery. Ty1, 2Rs15d, 2Rb17c, and nb22 nanobodies were employed to specifically recognize the large protein SARS-CoV-2 Spike, a medium-sized HER2 receptor, and the small protein murine urokinase-type plasminogen activator (muPA), respectively. The pores modified with…

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Nielsen, K. H. (2015). Regnemaskinen. In H. Kragh & K. H. Nielsen (Eds.), 50 opfindelser: Højdepunkter i teknologien (pp. 87-91). Aarhus Universitetsforlag.

Nielsen, K. H. (2015). Relativitet. Weekendavisen, Ideer, 10.

Eriksen, C. B., Wolfe, C. T. & Demarest, B. (2015). Review of Justin E. H. Smith: Divine Machines - Leibniz and the Sciences of Life. Journal of Early Modern Studies, 4(1), 128-132.

Xu, R., Liu, J., Chen, F., Liu, N., Cai, Y., Liu, X., Song, X., Dong, M. & Wang, L. (2015). Room-temperature tracking of chiral recognition process at the single-molecule level. Nano Research, 8(11), 3505-3511. https://doi.org/10.1007/s12274-015-0850-7

Knudsen, J. B., Liu, L., Kodal, A. L. B., Madsen, M., Li, Q., Song, J., Woehrstein, J., Wickham, S., Strauss, M., Schueder, F., Vinther, J., Krissanaprasit, A., Gudnason, D. A., Smith, A. A. A., Ogaki, R., Zelikin, A. N., Besenbacher, F., Birkedal, V., Yin, P. ... Gothelf, K. V. (2015). Routing of individual polymers in designed patterns. Nature Nanotechnology, 10, 892-898. https://doi.org/10.1038/nnano.2015.190

Nielsen, K. H. (2015). Samfundet. Weekendavisen, Ideer, 10.

Nielsen, K. H. (2015). Samlebåndet. In H. Kragh & K. H. Nielsen (Eds.), 50 opfindelser: Højdepunkter i teknologien (pp. 251-255). Aarhus Universitetsforlag.