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Recent research news on Artificial Biology

27 November 2023 - Research news

In this work, synthetic cells equipped with an artificial signaling pathway that connects an extracellular trigger event to the activation of intracellular transcription are engineered. Learning from nature, this is done via an engineering of responsive enzymes, such that activation of enzymatic activity can be triggered by an external biochemical stimulus. Reversibly deactivated creatine kinase to achieve triggered production of adenosine triphosphate, and a reversibly deactivated nucleic acid…

01 May 2023 - Research news

Nanopores are label-free single-molecule analytical tools that show great potential for stochastic sensing of proteins. Here, we described a ClyA nanopore functionalized with different nanobodies through a 5–6 nm DNA linker at its periphery. Ty1, 2Rs15d, 2Rb17c, and nb22 nanobodies were employed to specifically recognize the large protein SARS-CoV-2 Spike, a medium-sized HER2 receptor, and the small protein murine urokinase-type plasminogen activator (muPA), respectively. The pores modified with…

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Andersen, E. S. (2002). Kapitler i livets bog. Information.

Nielsen, K. H. (2002). M. J. Pasqualetti, P. Gipe, and R. W. Righter. Wind Power in View. Energy Landscapes in a Crowded World. Technology and Culture, 43(4), 825-826.

Andersen, E. S. (2002). Niles Eldredge - palæontologi og evolutionsteori. Pioneers in Biology 2002, 10-11.

Revsbech, N. P. & Finster, K. (2002). Oxygen: Effect on marine microbial communities. In Encyclopedia of Microbial Ecology (pp. 2277-2288). Wiley, New York.

Hein, J., Jensen, J. L. & Pedersen, C. N. S. (2002). Recursions for Statistical Multiple Alignment. Department of Mathematical Sciences , University of Aarhus.

Hein, J., Pedersen, C. N. S. & Jensen, J. L. (2002). Recursions for Statistical Multiple Alignment. Proceedings of the National Academy of Sciences (PNAS), 100(25), 14960-14965.

Dirac, A. M., Huthoff, H., Kjems, J. & Berkhout, B. (2002). Regulated HIV-2 RNA dimerization by means of alternative RNA conformation. Nucleic Acids Research, 30, 2647-2655.

A.M., D., H., H., Kjems, J. & B., B. (2002). Requirements for RNA-heterodimerization of the HIV-1 and HIV-2 genomes. Journal of General Virology, 83, 2533-2542.

Spillner, E. (2002). Selektion und Expression von rekombinanten Antikörpern für analytische und therapeutische Applikationen. Cuvillier Verlag.

Nørnberg, P., Merrison, J. P., Finster, K., Folkmann, F., Gunnlaugsson, H. P., Hansen, A., Jensen, A. M., Kinch, K., Lomstein, B. A. & Mugford, R. (2002). Simulation of martian surface conditions and dust transport. Paper presented at Graz, Austria, 16-19 September (ESA SP-518,November 2002).

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