Publications

Recent research news on Artificial Biology

27 November 2023 - Research news

In this work, synthetic cells equipped with an artificial signaling pathway that connects an extracellular trigger event to the activation of intracellular transcription are engineered. Learning from nature, this is done via an engineering of responsive enzymes, such that activation of enzymatic activity can be triggered by an external biochemical stimulus. Reversibly deactivated creatine kinase to achieve triggered production of adenosine triphosphate, and a reversibly deactivated nucleic acid…

01 May 2023 - Research news

Nanopores are label-free single-molecule analytical tools that show great potential for stochastic sensing of proteins. Here, we described a ClyA nanopore functionalized with different nanobodies through a 5–6 nm DNA linker at its periphery. Ty1, 2Rs15d, 2Rb17c, and nb22 nanobodies were employed to specifically recognize the large protein SARS-CoV-2 Spike, a medium-sized HER2 receptor, and the small protein murine urokinase-type plasminogen activator (muPA), respectively. The pores modified with…

Page 6 of 6

Recent publications by network

Sort by: Date | Author | Title

Seviour, T., Hansen, S. H., Yang, L., Yau, Y. H., Wang, V. B., Stenvang, M. R., Christiansen, G., Marsili, E., Givskov, M., Chen, Y., Otzen, D., Nielsen, P. H., Shochat, S. G., Kjelleberg, S. & Dueholm, M. S. (2015). Functional Amyloids Keep Quorum Sensing Molecules in Check. Journal of Biological Chemistry, 290, 6457-6469. https://doi.org/10.1074/jbc.M114.613810

Zeng, G., Vad, B. S., Dueholm, M. S., Christiansen, G., Nilsson, M., Tolker-Nielsen, T., Nielsen, P. H., Meyer, R. L. & Otzen, D. E. (2015). Functional bacterial amyloid increases Pseudomonas biofilm hydrophobicity and stiffness. Frontiers in Microbiology, 6, 1099. https://doi.org/10.3389/fmicb.2015.01099

Fowler, P. W., Orwick-Rydmark, M., Radestock, S., Solcan, N., Dijkman, P. M., Lyons, J. A., Kwok, J., Caffrey, M., Watts, A., Forrest, L. R. & Newstead, S. (2015). Gating topology of the proton-coupled oligopeptide symporters. Structure, 23(2), 290-301. https://doi.org/10.1016/j.str.2014.12.012

Nielsen, K. H. (2015). Gen. Weekendavisen, Ideer, 10.

Guo, Q., Xue, Q., Sun, J., Dong, M., Xia, F. & Zhang, Z. (2015). Gigantic enhancement in the dielectric properties of polymer-based composites using core/shell MWCNT/amorphous carbon nanohybrids. Nanoscale, 7(8), 3660-3667. https://doi.org/10.1039/c4nr05264a

Kyhl, L., Nielsen, S. F., Cabo, A. G., Cassidy, A., Miwa, J. A. & Hornekær, L. (2015). Graphene as an anti-corrosion coating layer. Faraday Discussions, 180, 495-509. https://doi.org/10.1039/c4fd00259h

Nielsen, K. H. (2015). Grønlands Tekniske Organisation. Videnskab.dk. http://videnskab.dk/blog/gronlands-tekniske-organisation