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Recent research news on Artificial Biology

27 November 2023 - Research news

In this work, synthetic cells equipped with an artificial signaling pathway that connects an extracellular trigger event to the activation of intracellular transcription are engineered. Learning from nature, this is done via an engineering of responsive enzymes, such that activation of enzymatic activity can be triggered by an external biochemical stimulus. Reversibly deactivated creatine kinase to achieve triggered production of adenosine triphosphate, and a reversibly deactivated nucleic acid…

01 May 2023 - Research news

Nanopores are label-free single-molecule analytical tools that show great potential for stochastic sensing of proteins. Here, we described a ClyA nanopore functionalized with different nanobodies through a 5–6 nm DNA linker at its periphery. Ty1, 2Rs15d, 2Rb17c, and nb22 nanobodies were employed to specifically recognize the large protein SARS-CoV-2 Spike, a medium-sized HER2 receptor, and the small protein murine urokinase-type plasminogen activator (muPA), respectively. The pores modified with…

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Bendtsen, K. L., Xu, K., Luckmann, M., Winther, K. S., Shah, S. A., Pedersen, C. N. S. & Brodersen, D. E. (2017). Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding. Nucleic Acids Research, 45(5), 2875-2886. https://doi.org/10.1093/nar/gkw1266

Hirsch, C., Jahnel, B., Keeler, P. & Patterson, R. IA. (2017). Traffic flow densities in large transport networks. Advances in Applied Probability, 49(4), 1091-1115.

Villadsen, N. L., Jacobsen, K. M., Tørring, T. & Poulsen, T. (2017). Unikke naturstoffer dræber resistente cancerceller. Dansk Kemi, 98(3), 10-13. http://ipaper.ipapercms.dk/TechMedia/DanskKemi/2017/3/

Lauritzen, L. & Nielsen, K. H. (2017). Vejrmagerne. Weekendavisen, Sektion 4 (Ideer), 13.

Nielsen, K. H. (2017). Viden. Weekendavisen, Sektion 4 (Ideer), 10.

Nielsen, K. H. (2017). Viden. Aarhus Universitetsforlag. Tænkepauser - viden til hverdagen Vol. 46

Zhang, Z., Xu, R., Wang, Z., Dong, M., Cui, B. & Chen, M. (2017). Visible Light Neural Stimulation on graphitic-Carbon Nitride/Graphene Photocatalytic Fibers. A C S Applied Materials and Interfaces, 9(40), 34736–34743. https://doi.org/10.1021/acsami.7b12733

Engholm, D. H., Goodsell, D., Kilian, M., Andersen, E. S., Pedersen, B. P. & Kjærgaard, R. S. (2017). Visualising the bacterium Streptococcus Pneumoniae. In L. Philipsen & R. Schmidt Kjærgaard (Eds.), The Aesthetics of Scientific Data Representation: More than Pretty Pictures Routledge. https://www.routledge.com/The-Aesthetics-of-Scientific-Data-Representation-More-than-Pretty-Pictures/Philipsen-Schmidt-Kjaergaard/p/book/9781138679375

Engholm, D. H., Goodsell, D., Kilian, M., Andersen, E. S., Pedersen, B. P. & Kjærgaard, R. S. (2017). Visualizing the Bacterium Streptococcus pneumoniae. In L. Philipsen & R. Schmidt Kjærgaard (Eds.), The Aesthetics of Scientific Data Representation: More than Pretty Pictures (1. ed. ed., pp. 1-15). Routledge. https://doi.org/10.4324/9781315563411

Bak, E. N., Goul, M., Rasmussen, M., Moeller, R., Nørnberg, P., Jensen, S. K. & Finster, K. (2017). Wind driven saltation: a hitherto overlooked challenge for life on Mars. Abstract from EGU 2017, Wien, Austria.

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