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AUNAB - Aarhus University Network on Artificial Biology

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Recent research news on Artificial Biology

27 November 2023 - Research news

In this work, synthetic cells equipped with an artificial signaling pathway that connects an extracellular trigger event to the activation of intracellular transcription are engineered. Learning from nature, this is done via an engineering of responsive enzymes, such that activation of enzymatic activity can be triggered by an external biochemical stimulus. Reversibly deactivated creatine kinase to achieve triggered production of adenosine triphosphate, and a reversibly deactivated nucleic acid…

01 May 2023 - Research news

Nanopores are label-free single-molecule analytical tools that show great potential for stochastic sensing of proteins. Here, we described a ClyA nanopore functionalized with different nanobodies through a 5–6 nm DNA linker at its periphery. Ty1, 2Rs15d, 2Rb17c, and nb22 nanobodies were employed to specifically recognize the large protein SARS-CoV-2 Spike, a medium-sized HER2 receptor, and the small protein murine urokinase-type plasminogen activator (muPA), respectively. The pores modified with…

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Rigau, L. H. & Stadler, B. M. (2013). Shear Stress and its Effect on the Interaction of Myoblast Cells with Nano-Sized Drug Delivery Vehicles. Molecular Pharmaceutics, 10(7), 2707-2712. https://doi.org/10.1021/mp4001298

Múzquiz, M. S., Bøjesen, E. D., Song, J., Dong, M. & Christensen, M. (2013). Size and shape control of magnetic hexaferrites.

Schiølin, K. H. (2013). Skærmkrigeren, døden og dronen. Baggrund. http://baggrund.com/skaermkrigeren-doden-og-dronen/

Nielsen, K. H. (2013). Slip videnskaben løs. Videnskab.dk. http://videnskab.dk/blog/slip-videnskaben-los

Basse-O'Connor, A. (2013). Some properties of a class of continuous time moving average processes. In Proceedings of the 18th European Young Statisticians Meeting J.J. Strossmayer University of Osijek.

Andersen, M. Ø., Le, D. Q. S., Chen, M., Nygaard, J. V., Kassem, M., Bünger, C. & Kjems, J. (2013). Spatially Controlled Delivery of siRNAs to Stem Cells in Implants Generated by Multi-Component Additive Manufacturing. Advanced Functional Materials, 23(45), 5599-5607. https://doi.org/10.1002/adfm.201300832

Kragh, H. & Nielsen, K. H. (2013). Spreading the gospel: A popular book on the Bohr atom in its historical context. Annals of Science, 70(2), 257-283. https://doi.org/10.1080/00033790.2012.695024

Schiølin, K. H. & Riis, S. (2013). Stævnemøde i München. Baggrund. http://baggrund.com/staevnemode-munchen/

Shen, C., Cramer, J. R., Jacobsen, M. F., Liu, L., Zhang, S., Dong, M., Gothelf, K. V. & Besenbacher, F. (2013). Steering supramolecular patterns by nucleobase-terminated molecules. Chemical Communications, 49(5), 508-510. https://doi.org/10.1039/c2cc37522b

Zhang, Y., Wang, W., Chen, J., Zhang, K., Gao, F., Gao, B., Zhang, S., Dong, M., Besenbacher, F., Gong, W., Zhang, M., Sun, F. & Feng, W. (2013). Structural Insights into the Intrinsic Self-Assembly of Par-3 N-Terminal Domain. Structure, 21(6), 997-1006. https://doi.org/10.1016/j.str.2013.04.004

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Kalinka Hansen