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AUNAB - Aarhus University Network on Artificial Biology

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Recent research news on Artificial Biology

27 November 2023 - Research news

In this work, synthetic cells equipped with an artificial signaling pathway that connects an extracellular trigger event to the activation of intracellular transcription are engineered. Learning from nature, this is done via an engineering of responsive enzymes, such that activation of enzymatic activity can be triggered by an external biochemical stimulus. Reversibly deactivated creatine kinase to achieve triggered production of adenosine triphosphate, and a reversibly deactivated nucleic acid…

01 May 2023 - Research news

Nanopores are label-free single-molecule analytical tools that show great potential for stochastic sensing of proteins. Here, we described a ClyA nanopore functionalized with different nanobodies through a 5–6 nm DNA linker at its periphery. Ty1, 2Rs15d, 2Rb17c, and nb22 nanobodies were employed to specifically recognize the large protein SARS-CoV-2 Spike, a medium-sized HER2 receptor, and the small protein murine urokinase-type plasminogen activator (muPA), respectively. The pores modified with…

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Fang, X., Wang, Z., Jiang, Z., Wang, J. & Dong, M. (2019). Coral-like S-doped CoSe₂ with enriched 1T-phase as efficient electrocatalyst for hydrogen evolution reaction. Electrochimica Acta, 322, Article 134739. https://doi.org/10.1016/j.electacta.2019.134739

Bregnhøj, M., Blázquez-Castro, A., Westberg, M., Breitenbach, T. & Ogilby, P. R. (2019). Correction to "Direct 765 nm Optical Excitation of Molecular Oxygen in Solution and in Single Mammalian Cells". Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical, 123(49), 10569-10569. https://doi.org/10.1021/acs.jpcb.9b10906

Nielsen, K. H. (2019). Cyberspace. Weekendavisen, Sektion 4 (Ideer), 10.

Nielsen, K. H. (2019). Data. Weekendavisen, Sektion 4 (Ideer), 10.

Meyer, R. L., Walther, R., Nielsen, S. M., Andersen, P. O., Hansen, L., Vu-Quang, H., Kjems, J. & Zelikin, A. N. (2019). Delivering antibiotics locally to biofilms by targeted drug delivery and prodrug therapy. Abstract from Eurobiofilms 2019, Glasgow, United Kingdom.

Valero Moreno, J., Centola, M., Ma, Y., Škugor, M., Yu, Z., Haydell, M. W., Keppner, D. & Famulok, M. (2019). Design, assembly, characterization, and operation of double-stranded interlocked DNA nanostructures. Nature Protocols, 14(10), 2818-2855. https://doi.org/10.1038/s41596-019-0198-7

Pantazidis, G., Scheffler, M., Simonsen, F. D. S., Cassidy, A., Jensen, P. A., Hornekær, L. & Thrower, J. D. (2019). Deuteration of C₆₀on a highly oriented pyrolytic graphite surface. Proceedings of the International Astronomical Union, 15(S356), 458-459. https://doi.org/10.1017/S1743921320000344

Wang, Z., Liu, X., Lu, Y., Wang, Z., Bortolini, C., Chen, M., Wei, S., Li, W., Zhu, J., Ju, H., Rosei, F., Dong, M. & Wang, L. (2019). Direct on-surface synthesis of gold-phthalocyanine: Via cyclization of cyano-groups with gold adatoms. Materials Chemistry Frontiers, 3(7), 1406-1410. https://doi.org/10.1039/c9qm00070d

Zhang, Z., Wang, J., Song, Y., Wang, Z., Dong, M. & Liu, L. (2019). Disassembly of Alzheimer's amyloid fibrils by functional upconversion nanoparticles under near-infrared light irradiation. Colloids and Surfaces B: Biointerfaces, 181, 341-348. https://doi.org/10.1016/j.colsurfb.2019.05.053

Fernández-Medina, M., Qian, X., Hovorka, O. & Städler, B. (2019). Disintegrating polymer multilayers to jump-start colloidal micromotors. Nanoscale, 11(2), 733-741. https://doi.org/10.1039/c8nr08071b

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Kalinka Hansen