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Recent research news on Artificial Biology

27 November 2023 - Research news

In this work, synthetic cells equipped with an artificial signaling pathway that connects an extracellular trigger event to the activation of intracellular transcription are engineered. Learning from nature, this is done via an engineering of responsive enzymes, such that activation of enzymatic activity can be triggered by an external biochemical stimulus. Reversibly deactivated creatine kinase to achieve triggered production of adenosine triphosphate, and a reversibly deactivated nucleic acid…

01 May 2023 - Research news

Nanopores are label-free single-molecule analytical tools that show great potential for stochastic sensing of proteins. Here, we described a ClyA nanopore functionalized with different nanobodies through a 5–6 nm DNA linker at its periphery. Ty1, 2Rs15d, 2Rb17c, and nb22 nanobodies were employed to specifically recognize the large protein SARS-CoV-2 Spike, a medium-sized HER2 receptor, and the small protein murine urokinase-type plasminogen activator (muPA), respectively. The pores modified with…

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Ebbesen, M. & Pedersen, B. D. (2007). Using Empirical Ethics to Formulate Normative Ethical Principles in Biomedicine. Medicine, Health Care and Philosophy, (1), 33-48.

Hansen, A. A., Herbert, R., Mikkelsen, K., Jensen, L. L., Kristoffersen, T., Tiedje, J. M., Lomstein, B. A. & Finster, K. (2007). Viability, diversity and composition of the bacterial community in a high Arctic permafrost soil from Spitsbergen, Northern Norway. Environmental Microbiology, 9(11), 2870-2884.

Dong, M., Howard, K. A., Oupicky, D., Bisht, H. J., Kjems, J. & Besenbacher, F. (2007). Visualisation of Thermal Activated Nanocarriers Using In Situ Atomic Force Microscopy. Nanotechnology.

Dong, M. D., Howard, K. A., Oupicky, D., Bisht, H., Kjems, J. & Besenbacher, F. (2007). Visualization of thermally activated nanocarriers using in situ atomic force microscopy: Nanotechnology. Nanotechnology, 18(18), Article 185501. https://doi.org/10.1088/0957-4484/18/18/185501

Otzen, D. & Nielsen, P. H. (2007). We find them here, we find them there: Functional bacterial amyloid. Cellular and Molecular Life Sciences, 65, 910-927.

Nielsen, K. H. (2006). 100 års videnskabsformidling. In R. S. Kjærgaard (Ed.), Elfenbenstårnet: Universiteter mellem forskning og formidling (pp. 35-54). Aarhus Universitetsforlag.

Dong, MD., Hovgaard, M. B., Xu, S., Otzen, D. E. & Besenbacher, F. (2006). AFM study of glucagon fibrillation via oligomeric structures resulting in interwoven fibrils. Nanotechnology, (17), 4003-4009.

Ebbesen, M. (2006). A Journey into the World of Atoms and Molecules. Journal of Lutheran Ethics , (2).

Jonstrup, S. P., Koch, J. & Kjems, J. (2006). A microRNA detection system based on padlock probes and rolling circle amplification. RNA, 12(9), 1747-1752. https://doi.org/10.1261/rna.110706

Nielsen, K. H. (2006). Anmeldelse af: Claus Holm: Forståelsens rasen (2005).

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