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Recent research news on Artificial Biology

27 November 2023 - Research news

In this work, synthetic cells equipped with an artificial signaling pathway that connects an extracellular trigger event to the activation of intracellular transcription are engineered. Learning from nature, this is done via an engineering of responsive enzymes, such that activation of enzymatic activity can be triggered by an external biochemical stimulus. Reversibly deactivated creatine kinase to achieve triggered production of adenosine triphosphate, and a reversibly deactivated nucleic acid…

01 May 2023 - Research news

Nanopores are label-free single-molecule analytical tools that show great potential for stochastic sensing of proteins. Here, we described a ClyA nanopore functionalized with different nanobodies through a 5–6 nm DNA linker at its periphery. Ty1, 2Rs15d, 2Rb17c, and nb22 nanobodies were employed to specifically recognize the large protein SARS-CoV-2 Spike, a medium-sized HER2 receptor, and the small protein murine urokinase-type plasminogen activator (muPA), respectively. The pores modified with…

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Engholm, D. H., Goodsell, D., Kilian, M., Andersen, E. S., Pedersen, B. P. & Kjærgaard, R. S. (2017). Visualizing the Bacterium Streptococcus pneumoniae. In L. Philipsen & R. Schmidt Kjærgaard (Eds.), The Aesthetics of Scientific Data Representation: More than Pretty Pictures (1. ed. ed., pp. 1-15). Routledge. https://doi.org/10.4324/9781315563411

Bak, E. N., Goul, M., Rasmussen, M., Moeller, R., Nørnberg, P., Jensen, S. K. & Finster, K. (2017). Wind driven saltation: a hitherto overlooked challenge for life on Mars. Abstract from EGU 2017, Wien, Austria.

van Diggelen, F., Tepper, A., Petri, M. & Otzen, D. (2017). α-Synuclein Oligomers: A Study in Diversity. Israel Journal of Chemistry, 57(7), 699-723. https://doi.org/10.1002/ijch.201600116

Nielsen, K. H. (2016). 1922 Atomet. In Danmark bliver moderne 1900-1950 Aarhus Universitetsforlag.

Nielsen, K. H. (2016). 1929 TV. In Danmark bliver moderne 1900-1950 Aarhus Universitetsforlag.

Nielsen, K. H. (2016). 1929 Universet. In Danmark bliver moderne 1900-1950 Aarhus Universitetsforlag.

Xu, R. & Chen, M. (2016). 3D Mechanical Environment and Chemical Cues Influence HUMC Fibroblast Differentiation and Fibroblast-To-Myofbiroblast Transition. Poster session presented at Advances in Cell Engineering, Imaging and Screening: VIB tools and technologies, Leuven, Belgium.

Zhang, Z., Chen, M. & Dong, MD. (2016). 3D Polymer Microfiber Architectures via Melt-electrospinning. Poster session presented at Advances in Cell Engineering, Imaging and Screening: VIB tools and technologies, Leuven, Belgium.

Nielsen, K. H. (2016). Åben adgang til forskning - en succes med få mislyde. Videnskab.dk.

Eriksen, C. B. (2016). Åbningen af den usynlige verden. Ny Jord - Tidsskrift for naturkritik, 2, 78-95.

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