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AUNAB - Aarhus University Network on Artificial Biology

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Recent research news on Artificial Biology

27 November 2023 - Research news

In this work, synthetic cells equipped with an artificial signaling pathway that connects an extracellular trigger event to the activation of intracellular transcription are engineered. Learning from nature, this is done via an engineering of responsive enzymes, such that activation of enzymatic activity can be triggered by an external biochemical stimulus. Reversibly deactivated creatine kinase to achieve triggered production of adenosine triphosphate, and a reversibly deactivated nucleic acid…

01 May 2023 - Research news

Nanopores are label-free single-molecule analytical tools that show great potential for stochastic sensing of proteins. Here, we described a ClyA nanopore functionalized with different nanobodies through a 5–6 nm DNA linker at its periphery. Ty1, 2Rs15d, 2Rb17c, and nb22 nanobodies were employed to specifically recognize the large protein SARS-CoV-2 Spike, a medium-sized HER2 receptor, and the small protein murine urokinase-type plasminogen activator (muPA), respectively. The pores modified with…

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Howard, K. (2013). Bioresponsive nanoparticles for the intracellular delivery of RNAi therapeutics. In Nanotechnology for the Delivery of Therapeutic Nucleic Acids (pp. 129-151). Pan Stanford Publishing. https://doi.org/10.4032/9789814411059

Nielsen, K. H. (2013). Bohr-atomet i populær indbinding. Kvant: Tidsskrift for Fysik og Astronomi, 24(December), 22-24.

Nielsen, K. H. (2013). Bohr-atomets mange iklædninger. Videnskab.dk. http://videnskab.dk/blog/bohr-atomets-mange-iklaedninger

Nilsson, L., Andersen, M., Hammer, B., Stensgaard, I. & Hornekær, L. (2013). Breakdown of the Graphene Coating Effect under Sequential Exposure to O₂ and H₂S. The Journal of Physical Chemistry Letters, 4(21), 3770-3774. https://doi.org/10.1021/jz402054e

Madsen, M. E. L., Mian Teo, B., Laursen, M. B., Zhang, Y. & Stadler, B. (2013). Cargo delivery to adhering myoblast cells from liposome-containing poly(dopamine) composite coatings. Journal of Biomaterials Science. Polymer Edition, 1(11), 1181-1192. https://doi.org/10.1039/C3BM60107B

Mian Teo, B., van der Westen, R., Rigau, L. H. & Stadler, B. M. (2013). Cell Response to PEGylated Poly(dopamine) Coated Liposomes Considering Shear Stress. B B A - General Subjects, (10), 4838-4847. https://doi.org/10.1016/j.bbagen.2013.06.022

Sükösd, Z., Knudsen, B., Anderson, J. WJ., Novák, A., Kjems, J. & Pedersen, C. N. S. (2013). Characterising RNA secondary structure space using information entropy. BMC Bioinformatics, 14 (Suppl 2), 1-9. Article S22. https://doi.org/10.1186/1471-2105-14-S2-S22

Basse-O'Connor, A. & Rosiński, J. (2013). Characterization of the finite variation property for a class of stationary increment infinitely divisible processes. Stochastic Processes and Their Applications, 123(6), 1871-1890. https://doi.org/10.1016/j.spa.2013.01.014

Rigau, L. H., Zhang, Y., Mian Teo, B., Postma, A. & Stadler, B. M. (2013). Cholesterol: A Biological Compound as Building Block in Bionanotechnology. Nanoscale, (5), 89-109. https://doi.org/10.1039/C2NR32923A

Rasmussen, K. F., Smith, A. A. A., Ruiz-Sanchis, P., Edlund, K. & Zelikin, A. N. (2013). Cholesterol Modification of (Bio)Polymers Using UV-Vis Traceable Chemistry in Aqueous Solutions. Macromolecular Bioscience, 14(1), 33-44. https://doi.org/10.1002/mabi.201300286

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Kalinka Hansen