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AUNAB - Aarhus University Network on Artificial Biology

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Recent research news on Artificial Biology

27 November 2023 - Research news

In this work, synthetic cells equipped with an artificial signaling pathway that connects an extracellular trigger event to the activation of intracellular transcription are engineered. Learning from nature, this is done via an engineering of responsive enzymes, such that activation of enzymatic activity can be triggered by an external biochemical stimulus. Reversibly deactivated creatine kinase to achieve triggered production of adenosine triphosphate, and a reversibly deactivated nucleic acid…

01 May 2023 - Research news

Nanopores are label-free single-molecule analytical tools that show great potential for stochastic sensing of proteins. Here, we described a ClyA nanopore functionalized with different nanobodies through a 5–6 nm DNA linker at its periphery. Ty1, 2Rs15d, 2Rb17c, and nb22 nanobodies were employed to specifically recognize the large protein SARS-CoV-2 Spike, a medium-sized HER2 receptor, and the small protein murine urokinase-type plasminogen activator (muPA), respectively. The pores modified with…

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Recent publications by network

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Nielsen, K. H. (2019). 5G. Weekendavisen, Sektion 4 (Ideer), 10.

Yang, Q., Wang, Z., Dong, L., Zhao, W., Jin, Y., Fang, L., Hu, B. & Dong, M. (2019). Activating MoS ₂ with Super-High Nitrogen-Doping Concentration as Efficient Catalyst for Hydrogen Evolution Reaction. Journal of Physical Chemistry C, 123(17), 10917-10925. https://doi.org/10.1021/acs.jpcc.9b00059

Nielsen, K. H. (2019). Aforisme. Weekendavisen, Sekton 4 (Ideer), 10.

Speed, M., Balding, D. J. & Hobolth, A. (2019). A general framework for moment-based analysis of genetic data. Journal of Mathematical Biology, 78(6), 1727-1769. https://doi.org/10.1007/s00285-018-01325-0

Nielsen, K. H. (2019). Akratisk. Weekendavisen, Sektion 4 (Ideer), 10.

Thomsen, R. P., Malle, M. G., Okholm, A. H., Krishnan, S., Bohr, S. S. R., Sørensen, R. S., Ries, O., Vogel, S., Simmel, F. C., Hatzakis, N. S. & Kjems, J. (2019). A large size-selective DNA nanopore with sensing applications. Nature Communications, 10(1), Article 5655. https://doi.org/10.1038/s41467-019-13284-1

Nissen, S. K., Shrivastava, K., Schulte, C., Otzen, D. E., Goldeck, D., Berg, D., Møller, H. J., Maetzler, W. & Romero-Ramos, M. (2019). Alterations in Blood Monocyte Functions in Parkinson's Disease. Movement Disorders, 34(11), 1711-1721. https://doi.org/10.1002/mds.27815

Tian, X., Sha, X., Feng, Y., Duan, Y., Dong, M., Liu, L. & Pan, G. (2019). A Magnetic Dynamic Microbiointerface with Biofeedback Mechanism for Cancer Cell Capture and Release. ACS Applied Materials & Interfaces, 11(44), 41019-41029. https://doi.org/10.1021/acsami.9b13140

Cui, X., Cheng, W., Dong, M. & Han, X. (2019). A multifunctional biomimetic hybrid nanocarrier for the controlled delivery of chemotherapy drugs by near-infrared light. New Journal of Chemistry, 43(6), 2752-2757. https://doi.org/10.1039/C8NJ05879B

Schelde, K. K., Nicholls , K., Dagnæs-Hansen, F., Bunting , K., Rawsthorne, H., Andersen, B., Finnis, C., Williamson, M., Cameron, J. & Howard, K. (2019). A new class of recombinant human albumin with multiple surface thiols exhibit stable conjugation, and enhanced FcRn binding and blood circulation. Journal of Biological Chemistry, 294(10), 3735-3743. https://doi.org/10.1074/jbc.RA118.005870

Displaying results 1081 to 1090 out of 3460

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Kalinka Hansen