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AUNAB - Aarhus University Network on Artificial Biology

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Recent research news on Artificial Biology

27 November 2023 - Research news

In this work, synthetic cells equipped with an artificial signaling pathway that connects an extracellular trigger event to the activation of intracellular transcription are engineered. Learning from nature, this is done via an engineering of responsive enzymes, such that activation of enzymatic activity can be triggered by an external biochemical stimulus. Reversibly deactivated creatine kinase to achieve triggered production of adenosine triphosphate, and a reversibly deactivated nucleic acid…

01 May 2023 - Research news

Nanopores are label-free single-molecule analytical tools that show great potential for stochastic sensing of proteins. Here, we described a ClyA nanopore functionalized with different nanobodies through a 5–6 nm DNA linker at its periphery. Ty1, 2Rs15d, 2Rb17c, and nb22 nanobodies were employed to specifically recognize the large protein SARS-CoV-2 Spike, a medium-sized HER2 receptor, and the small protein murine urokinase-type plasminogen activator (muPA), respectively. The pores modified with…

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Recent publications by network

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Nielsen, K. H. (2018). Statistik. Weekendavisen, Sektion 4 (Ideer), 10.

Nielsen, K. H. & Zilhão, I. (2018). Stem Frenzy: teaching science to children and young people, 1815-1991. Cambridge Core Blog. http://blog.journals.cambridge.org/2018/09/07/stem-frenzy-teaching-science-to-children-and-young-people-1815-1991/

Villadsen, N. L., Hansen, B. K., Svenningsen, E. B., Jørgensen, K. H., Tørring, T. & Poulsen, T. B. (2018). Stendomycin and Pantomycin Are Identical Natural Products: Preparation of a Functionalized Bioactive Analogue. Journal of Organic Chemistry, 83(13), 7303-7308. https://doi.org/10.1021/acs.joc.8b00553

Kang, H., Qian, X., Guan, L., Zhang, M., Li, Q., Wu, A. & Dong, M. (2018). Studying the Adhesion Force and Glass Transition of Thin Polystyrene Films by Atomic Force Microscopy. Nanoscale Research Letters, 13(5), Article 5. https://doi.org/10.1186/s11671-017-2426-9

Nielsen, K. H. (2018). Styr STEM-begejstringen. Science Report.

Kang, R., Li, H., Peng, X., Ringgaard, S., Baatrup, A., Rickers, K., Sun, M., Le, D. Q. S., Wang, M., Xie, L., Chen, M. & Bünger, C. (2018). Surgical Repair of Annulus Defect with Biomimetic Multilamellar Nano/microfibrous Scaffold in a Porcine Model. Journal of Tissue Engineering and Regenerative Medicine, 12(1), 164-174. https://doi.org/10.1002/term.2384

Nielsen, K. H. (2018). Sygdom. Weekendavisen, Sektion 4 (Ideer), 10.

Wang, X., Sun, F., Yin, G., Wang, Y., Liu, B. & Dong, M. (2018). Tactile-sensing based on flexible PVDF nanofibers via electrospinning: A review. Sensors (Switzerland), 18(2), Article 330. https://doi.org/10.3390/s18020330

Moein Moghimi, S. & Howard, K. (2018). Targeting Biological Barriers. Molecular Therapy, 26(4), 933-934. https://doi.org/10.1016/j.ymthe.2018.03.008

Nielsen, K. H. (2018). Teknologi. Weekendavisen, Sektion 4 (Ideer), 10.

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Kalinka Hansen