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AUNAB - Aarhus University Network on Artificial Biology

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Recent research news on Artificial Biology

27 November 2023 - Research news

In this work, synthetic cells equipped with an artificial signaling pathway that connects an extracellular trigger event to the activation of intracellular transcription are engineered. Learning from nature, this is done via an engineering of responsive enzymes, such that activation of enzymatic activity can be triggered by an external biochemical stimulus. Reversibly deactivated creatine kinase to achieve triggered production of adenosine triphosphate, and a reversibly deactivated nucleic acid…

01 May 2023 - Research news

Nanopores are label-free single-molecule analytical tools that show great potential for stochastic sensing of proteins. Here, we described a ClyA nanopore functionalized with different nanobodies through a 5–6 nm DNA linker at its periphery. Ty1, 2Rs15d, 2Rb17c, and nb22 nanobodies were employed to specifically recognize the large protein SARS-CoV-2 Spike, a medium-sized HER2 receptor, and the small protein murine urokinase-type plasminogen activator (muPA), respectively. The pores modified with…

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Recent publications by network

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Pfeffer, C., Larsen, S., Song, J., Dong, M., Besenbacher, F., Meyer, R. L., Kjeldsen, K. U., Schreiber, L., Gorby, Y. A., El-Naggar, M. Y., Leung, K. M., Schramm, A., Risgaard-Petersen, N. & Nielsen, L. P. (2012). Filamentous bacteria transport electrons over centimetre distances. Nature, 491, 218-221. https://doi.org/10.1038/nature11586

Schiølin, K. H. (2012). Follow the verbs! A Contribution to the Study of the Heidegger–Latour Connection. Social Studies of Science, 42(5), 776-787. https://doi.org/10.1177/0306312712448441

Kötzler, M. P., Blank, S., Behnken, H. N., Alpers, D., Bantleon, F. I., Spillner, E. & Meyer, B. (2012). Formation of the immunogenic α1,3-fucose epitope: elucidation of substrate specificity and of enzyme mechanism of core fucosyltransferase A. Insect Biochemistry and Molecular Biology, 42(2), 116-25. https://doi.org/10.1016/j.ibmb.2011.11.004

Nielsen, K. H. (2012). Forskningsansøgninger – hvordan bedømmes de bedst? Videnskab.dk. http://videnskab.dk/blog/forskningsansogninger-hvordan-bedommes-de-bedst

Nielsen, K. H. (2012). Forskningskommunikation 2.0. Videnskab.dk. http://videnskab.dk/blog/forskningskommunikation-20

Nielsen, K. H. (2012). Forskningsspin. Videnskab.dk. http://videnskab.dk/blog/forskningsspin

Jensen, S. M. R., Schmitz, A., Pedersen, F. S., Kjems, J. & Bramsen, J. B. (2012). Functional selection of shRNA loops from randomized retroviral libraries. PLoS One, 7(8), e43095. https://doi.org/10.1371/journal.pone.0043095

Ebbesen, M., Andersen, S. & Pedersen, B. D. (2012). Further Development of Beauchamp and Childress' Theory Based on Empirial Ethics. Journal of Clinical Research and Bioethics, (S6:e001), 1-7. https://doi.org/10.4172/2155-9627.S6-e001

Barcena, T. G., Finster, K. & Yde, J. C. (2012). Gletscheres ekstreme økosystemer og deres respons på klimaændringer. Geologisk Nyt, 24-25.

Nilsson, L., Andersen, M., Balog, R., Lægsgaard, E., Hofmann, P., Besenbacher, F., Hammer, B., Stensgaard, I. & Hornekær, L. (2012). Graphene Coatings: Probing the Limits of the One Atom Thick Protection Layer. A C S Nano, 6(11), 10258–10266. https://doi.org/10.1021/nn3040588

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Kalinka Hansen