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Recent research news on Artificial Biology

27 November 2023 - Research news

In this work, synthetic cells equipped with an artificial signaling pathway that connects an extracellular trigger event to the activation of intracellular transcription are engineered. Learning from nature, this is done via an engineering of responsive enzymes, such that activation of enzymatic activity can be triggered by an external biochemical stimulus. Reversibly deactivated creatine kinase to achieve triggered production of adenosine triphosphate, and a reversibly deactivated nucleic acid…

01 May 2023 - Research news

Nanopores are label-free single-molecule analytical tools that show great potential for stochastic sensing of proteins. Here, we described a ClyA nanopore functionalized with different nanobodies through a 5–6 nm DNA linker at its periphery. Ty1, 2Rs15d, 2Rb17c, and nb22 nanobodies were employed to specifically recognize the large protein SARS-CoV-2 Spike, a medium-sized HER2 receptor, and the small protein murine urokinase-type plasminogen activator (muPA), respectively. The pores modified with…

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Fredslund, J. & Andersen, E. S. (2005). Superjordnøddernes hemmelighed. Aktuel Naturvidenskab, (6), 12-15.

Sehgal, P., Doe, H., Sharma, M. & Otzen, D. E. (2005). Synergistic behavior of sodiumdodecylsulfate and 1,2-diheptanoyl-sn- glycero-3-phosphocholine in an aqueous medium: Interfacial and bulk behavior. Colloid and Polymer Science, 283(11), 1219-1225. https://doi.org/10.1007/s00396-005-1315-4

Møller, J. V., Nissen, P., Sørensen, T. L.-M. & le Maire, M. (2005). Transport mechanism of the sarcoplasmic reticulum Ca2+ATPase pump. Curr. Op. Struct. Biol., 15, 387-393.

Sehgal, P., Mogensen, J. E. & Otzen, D. (2005). Using micellar mole fractions to assess membrane protein stability in mixed micelles. Biochimica et biophysica acta - Biomembranes, 1761, 59-68. https://doi.org/10.1016/j.bbamem.2005.08.006

Kaufmann, I., Keiding, S. R. & Andersen, E. S. (2005). Viden om vand. Aarhus Universitetsforlag.

Nielsen, K. H. (2005). Visita a la exposición 'Making Things Public. Atmospheres of Democracy'. (Center for Art and Media, Karlsruhe. Alemania). AIBR Revista de Antropología. http://www.plazamayor.net/antropologia/44nov/cronicas/nov0502.pdf

Nielsen, K. H. (2004). 1:1 - Hvordan Danmark kom til at ligne Danmarkskortet. Kulturo.

Jakobsen, M. R., Damgaard, C. K., Andersen, E. S., Podhajska, A. & Kjems, J. (2004). A genomic selection strategy to identify accessible and dimerization blocking targets in the 5'-UTR of HIV-1 RNA. Nucleic Acids Research, 32(7), e67. https://doi.org/10.1093/nar/gnh064

Nygaard, J. V., Andersen, M. Ø., Howard, K., Sasov, A., Kjems, J. & Besenbacher, F. (2004). Analysis of Nanoparticles in Scaffolds for Tissue Engineering by use of X-Ray Nano Tomography. Poster session presented at iNANO 4^th annual meeting, Aarhus, Denmark.

Neubauer, A. T. A., Pedersen, A.-GU., Finster, K., Herbert, R. A., Donelly, A. P., Viaroli, P., Giordani, G., de Wit, R. & Lomstein, B. A. (2004). Benthic decomposition of Zostera marina roots: a controlled laboratory experiment. Journal of Experimental Marine Biology and Ecology, 313, 105-124.

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