Publications

Recent research news on Artificial Biology

Distinct Network Morphologies from In Situ Polymerization of Microtubules in Giant Polymer-Lipid Hybrid Vesicles

Creating artificial cells with a dynamic cytoskeleton, akin to those in living cells, is a major goal in bottom-up synthetic biology. In this study, we demonstrate the in situ polymerization of microtubules encapsulated in giant polymer-lipid hybrid vesicles (GHVs) composed of 1,2-dioleoyl-sn-glycero-3-phosphocholine and an amphiphilic block copolymer. The block copolymer is comprised of poly(cholesteryl methacrylate-co-butyl methacrylate) as the hydrophobic block and either poly(6-O-methacryloyl-D-galactopyranose) or poly(carboxyethyl acrylate) as the hydrophilic extension. Depending on the concentrations of guanosine triphosphate (GTP) or its slowly hydrolyzable analog, guanosine-5′-[(α,β)-methyleno]triphosphate (GMPCPP), different microtubule morphologies are observed, including encapsulated microtubule networks, spike protrusions, as well as membrane-associated or aggregated microtubules. Overall, this work represents a step forward in mimicking the cellular cytoskeletons and uncovering the influence of membrane composition on microtubule morphologies.

Recent publications by network

Sort by: Date | Author | Title

Hirsch, C. P., Otto, M. & Svane, A. M. (2024). NORMAL APPROXIMATION FOR GIBBS PROCESSES VIA DISAGREEMENT COUPLINGS. https://doi.org/10.1214/25-EJP1351

Wang, J., Zhang, W., Wu, T., Chen, M. & Dong, M. (2024). Occurrence of giant plasma bubble in liquid. Matter, 7(9), 3024-3035. https://doi.org/10.1016/j.matt.2024.04.032

Botnan, M. B. & Hirsch, C. (2024). On the consistency and asymptotic normality of multiparameter persistent Betti numbers. Journal of Applied and Computational Topology, 8(6), 1465-1502. https://doi.org/10.1007/s41468-022-00110-9

Lagido, C., Nielsen, K. H., Kragh, G., Flohr, P., Bezuidenhout, L., Brinkman, L., Baini, A., Saviane, C., Salnikova, A., Brandstetter-Kunc, A., Consolini, G., Correia, A., Moura, P., Fedeli, M., England, J., Venkataraman, S., Skarvøy, A., Konach, T., Taraj, B. ... Haklay, M. (2024). Open Educational Resources on Open Science and Responsible Research and Innovation (Open RRI). In EDULEARN24 Proceedings: 16th International Conference on Education and New Learning Technologies Palma, Spain. 1-3 July, 2024 (pp. 6745-6751). International Association of Technology, Education and Development (IATED). https://doi.org/10.21125/edulearn.2024.1601

Xin, Z., Kou, J., Luo, M., Liu, Q., Carraro, M., Dong, M., Daasbjerg, K., Skrydstrup, T. & Huang, Y. (2024). Open frame-like Co-Fe oxides superstructures for highly efficient cross-dehydrogenative coupling reaction of N-phenyltetrahydroisoquinoline under mild conditions. Inorganic Chemistry Communications, 170(2), Article 113352. https://doi.org/10.1016/j.inoche.2024.113352

Nielsen, K. H. (2024). Operation flere babyer. Weekendavisen, Sektion 4 (Ideer), 5.

Xiong, X., Wu, F., Ouyang, Y., Liu, Y., Wang, Z., Tian, H. & Dong, M. (2024). Oxygen Incorporated MoS₂ for Rectification-Mediated Resistive Switching and Artificial Neural Network. Advanced Functional Materials, 34(15), Article 2213348. https://doi.org/10.1002/adfm.202213348

Peeters, E., Habart, E., Berné, O., Sidhu, A., Chown, R., Van De Putte, D., Trahin, B., Schroetter, I., Canin, A., Alarcón, F., Schefter, B., Khan, B., Pasquini, S., Tielens, A. G. G. M., Wolfire, M. G., Dartois, E., Goicoechea, J. R., Maragkoudakis, A., Onaka, T. ... Zhen, J. (2024). PDRs4All: III. JWST's NIR spectroscopic view of the Orion Bar. Astronomy and Astrophysics, 685, Article A74. https://doi.org/10.1051/0004-6361/202348244

Chown, R., Sidhu, A., Peeters, E., Tielens, A. G. G. M., Cami, J., Berné, O., Habart, E., Alarcón, F., Canin, A., Schroetter, I., Trahin, B., Van De Putte, D., Abergel, A., Bergin, E. A., Bernard-Salas, J., Boersma, C., Bron, E., Cuadrado, S., Dartois, E. ... Zhen, J. (2024). PDRs4All: IV. An embarrassment of riches: Aromatic infrared bands in the Orion Bar. Astronomy and Astrophysics, 685, Article A75. https://doi.org/10.1051/0004-6361/202346662

Habart, E., Peeters, E., Berné, O., Trahin, B., Canin, A., Chown, R., Sidhu, A., De Putte, D. V., Alarcón, F., Schroetter, I., Dartois, E., Vicente, S., Abergel, A., Bergin, E. A., Bernard-Salas, J., Boersma, C., Bron, E., Cami, J., Cuadrado, S. ... Zhen, J. (2024). PDRs4All II. JWST’s NIR and MIR imaging view of the Orion Nebula. Astronomy and Astrophysics, 685, Article A73. https://doi.org/10.1051/0004-6361/202346747

Displaying results 331 to 340 out of 3464