AUNAB - Aarhus University Network on Artificial Biology

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Recent research news on Artificial Biology

Actin-Powered Motors Build Cytoskeletons in Artificial Cells

AUNAB members Assistant Prof. Miguel Ramos Docampo's and Prof. Brigitte Stadler's effort to engineered artificial cells to form cytoskeleton-like networks using nanomotor-driven actin polymerization is published in ACS Nano. These hybrid vesicles merge active matter with synthetic biology to achieve life-like movement and self-organization inspired by Listeria’s actin-based propulsion.

 

 

Read the article published in ACS Nano here.

Contact information:
Professor Brigitte Maria Städler
Aarhus University
Interdisciplinary Nanoscience Center (iNANO)
Email: bstadler@inano.au.dk

Assistant Professor Miguel Alexandre Ramos Docampo
Aarhus University
Interdisciplinary Nanoscience Center (iNANO)
Email: miramos@inano.au.dk

Recent publications by network

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Søkilde, R., Kaadt, E., Kristensen, L. S., Venø, M. T., Kjems, J., Nyengaard, J. R., Nielsen, B. S. & Elfving, B. (2025). Application of microRNA In Situ Hybridization on Long-term Stored Human Formalin-fixed Paraffin-embedded Brain Samples from Psychiatric Patients. Molecular Neurobiology, 62(10), 12736-12746. https://doi.org/10.1007/s12035-025-05077-z
Kriebisch, C. M. E., Bantysh, O., Baranda Pellejero, L., Belluati, A., Bertosin, E., Dai, K., de Roy, M., Fu, H., Galvanetto, N., Gibbs, J. M., Gomez, S. S., Granatelli, G., Griffo, A., Guix, M., Gurdap, C. O., Harth-Kitzerow, J., Haugerud, I. S., Häfner, G., Jaiswal, P. ... Boekhoven, J. (2025). A roadmap toward the synthesis of life. Chem, 11(3), Article 102399. https://doi.org/10.1016/j.chempr.2024.102399
Makhaik, S., Rut, W., Choudhary, S., Upadhyay, T., Hao, C., Westberg, M., Bobst, C., Yoo, E., Fejzo, J., Lin, M. Z., Bogyo, M., Thompson, P., Drag, M. & Hardy, J. A. (2025). A robust fluorogenic substrate for chikungunya virus protease (nsP2) activity. Protein Science, 34(3), Article e70069. https://doi.org/10.1002/pro.70069
Städler, B., Zelikin, A. N., Valero, J., Andersen, E. S. & Sánchez, S. (2025). Artificial Biology - Assemble, Imitate, Adapt. Advanced Biology, 9(5), Article 2500236. https://doi.org/10.1002/adbi.202500236
Søgaard, A. B., Hansson, R. F., Nielsen, M. H. & Zelikin, A. N. (2025). Artificial Internalizing Receptors for Targeted Degradation of Extracellular Proteins. Advanced Science, 12(37), Article e09083. https://doi.org/10.1002/advs.202509083
Zhang, L., Bai, J., Shen, A., Zhao, J., Su, Z., Wang, M., Dong, M. & Xu, Z. P. (2025). Artificially tagging tumors with nano-aluminum adjuvant-tethered antigen mRNA recruits and activates antigen-specific cytotoxic T cells for enhanced cancer immunotherapy. Biomaterials, 317, Article 123085. https://doi.org/10.1016/j.biomaterials.2025.123085
Søgaard, A. B., Løvschall, K. B., Montasell, M. C., Cramer, C. B., Marcet, P. M., Pedersen, A. B., Jakobsen, J. H. & Zelikin, A. N. (2025). Artificial Receptor in Synthetic Cells Performs Transmembrane Activation of Proteolysis. Advanced Biology, 9(5), Article 2400053. https://doi.org/10.1002/adbi.202400053
Castenschiold, C. D. F., Mignani, C., Christiansen, S., Alsved, M., Ickes, L., Tesson, S. V. M., Löndahl, J., Bilde, M., Bataillon, T., Finster, K. & Šantl-Temkiv, T. (2025). Atmospheric Biogenic Ice-Nucleating Particles Link to Microbial Communities in the Arctic Marine Environment in Western Greenland. Environmental Science and Technology, 59(42), 22518-22532. https://doi.org/10.1021/acs.est.5c03650
Samanta, A., Malle, M. G., Tsang, E., Omer, M., Skaanning, M. K., Kjems, J. & Gothelf, K. V. (2025). Bacteriophage-Mimetic DNA Origami Needle for Targeted Membrane Penetration and Cytosolic Cargo Delivery. bioRxiv. https://doi.org/10.1101/2025.06.16.659898
Nielsen, K. H. (2025). Beklager, ikke forstået. Weekendavisen, Sektion 4 (Ideer), 5.

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Revised 03.03.2026
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Kalinka Hansen