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AUNAB - Aarhus University Network on Artificial Biology

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Recent research news on Artificial Biology

Actin-Powered Motors Build Cytoskeletons in Artificial Cells

AUNAB members Assistant Prof. Miguel Ramos Docampo's and Prof. Brigitte Stadler's effort to engineered artificial cells to form cytoskeleton-like networks using nanomotor-driven actin polymerization is published in ACS Nano. These hybrid vesicles merge active matter with synthetic biology to achieve life-like movement and self-organization inspired by Listeria’s actin-based propulsion.

16 October 2025 by Emilia Djomina Hansen

Read the article published in ACS Nano here.

Contact information:
Professor Brigitte Maria Städler
Aarhus University
Interdisciplinary Nanoscience Center (iNANO)
Email: bstadler@inano.au.dk

Assistant Professor Miguel Alexandre Ramos Docampo
Aarhus University
Interdisciplinary Nanoscience Center (iNANO)
Email: miramos@inano.au.dk

Recent publications by network

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Fuchs, E., Rudnik-Jansen, I., Dinesen, A., Selnihhin, D., Mandrup, O. A., Thiam, K., Kjems, J., Pedersen, F. S. & Howard, K. A. (2022). An albumin-angiotensin converting enzyme 2-based SARS-CoV-2 decoy with FcRn-driven half-life extension. Acta Biomaterialia, 153, 411-418. https://doi.org/10.1016/j.actbio.2022.09.048

Dinesen, A., Winther, A., Wall, A., Märcher, A., Palmfeldt, J., Chudasama, V., Wengel, J., Gothelf, K. V., Baker, J. R. & Howard, K. (2022). An Albumin Biomolecular Drug Design Stabilized through Improved Thiol Conjugation and a Modular Locked Nucleic Acid Assembly. Poster session presented at Controlled Release Society 2022 Annual Meeting, Montreal, Quebec, Canada.

He, J., Steffen, J. H., Thulstrup, P. W., Pedersen, J. N., Sauerland, M. B., Otzen, D. E., Hawkins, C. L., Gourdon, P., Davies, M. J. & Hägglund, P. (2022). Anastellin impacts on the processing of extracellular matrix fibronectin and stimulates release of cytokines from coronary artery smooth muscle cells. Scientific Reports, 12(1), Article 22051. https://doi.org/10.1038/s41598-022-26359-9

Rajabi-Abhari, A., Lee, J., Tabassian, R., Kim, J.-N., Lee, H. & Oh, I.-K. (2022). Antagonistically Functionalized Diatom Biosilica for Bio-Triboelectric Generators. Small, 18(20), Article 2107638. https://doi.org/10.1002/smll.202107638

Ali, I. H., Ouf, A., Elshishiny, F., Taskin, M. B., Song, J., Dong, M., Chen, M., Siam, R. & Mamdouh, W. (2022). Antimicrobial and Wound-Healing Activities of Graphene-Reinforced Electrospun Chitosan/Gelatin Nanofibrous Nanocomposite Scaffolds. ACS Omega, 7(2), 1838-1850. https://doi.org/10.1021/acsomega.1c05095

Pirhaghi, M., Frank, S. A., Alam, P., Nielsen, J., Sereikaite, V., Gupta, A., Strømgaard, K., Andreasen, M., Sharma, D., Saboury, A. A. & Otzen, D. E. (2022). A penetratin-derived peptide reduces the membrane permeabilization and cell toxicity of α-synuclein oligomers. Journal of Biological Chemistry, 298(12), Article 102688. https://doi.org/10.1016/j.jbc.2022.102688

Mohammad-Beigi, H., Zanganeh, M., Scavenius, C., Eskandari, H., Farzadfard, A., Shojaosadati, S. A., Enghild, J. J., Otzen, D. E., Buell, A. K. & Sutherland, D. S. (2022). A Protein Corona Modulates Interactions of α-Synuclein with Nanoparticles and Alters the Rates of the Microscopic Steps of Amyloid Formation. ACS Nano, 16(1), 1102-1118. https://doi.org/10.1021/acsnano.1c08825

Ommen, P., Hansen, L., Hansen, B. K., Vu-Quang, H., Kjems, J. & Meyer, R. L. (2022). Aptamer-Targeted Drug Delivery for Staphylococcus aureus Biofilm. Frontiers in cellular and infection microbiology, 12, Article 814340. https://doi.org/10.3389/fcimb.2022.814340

Kim, B. B., Wu, H., Hao, Y. A., Pan, M., Chavarha, M., Zhao, Y., Westberg, M., St-Pierre, F., Wu, J. C. & Lin, M. Z. (2022). A red fluorescent protein with improved monomericity enables ratiometric voltage imaging with ASAP3. Scientific Reports, 12(1), Article 3678. https://doi.org/10.1038/s41598-022-07313-1

Laursen, R. & Hobolth, A. (2022). A Sampling Algorithm to Compute the Set of Feasible Solutions for NonNegative Matrix Factorization with an Arbitrary Rank. SIAM Journal on Matrix Analysis and Applications, 43(1), 257-273. https://doi.org/10.1137/20M1378971

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Kalinka Hansen