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AUNAB - Aarhus University Network on Artificial Biology

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Recent research news on Artificial Biology

Actin-Powered Motors Build Cytoskeletons in Artificial Cells

AUNAB members Assistant Prof. Miguel Ramos Docampo's and Prof. Brigitte Stadler's effort to engineered artificial cells to form cytoskeleton-like networks using nanomotor-driven actin polymerization is published in ACS Nano. These hybrid vesicles merge active matter with synthetic biology to achieve life-like movement and self-organization inspired by Listeria’s actin-based propulsion.

16 October 2025 by Emilia Djomina Hansen

Read the article published in ACS Nano here.

Contact information:
Professor Brigitte Maria Städler
Aarhus University
Interdisciplinary Nanoscience Center (iNANO)
Email: bstadler@inano.au.dk

Assistant Professor Miguel Alexandre Ramos Docampo
Aarhus University
Interdisciplinary Nanoscience Center (iNANO)
Email: miramos@inano.au.dk

Recent publications by network

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Civit, L., Moradzadeh, N., Jonczyk, A., Neckermann, P., Asbach, B., Peterhoff, D., Wagner, R., Famulok, M., Mayer, G., Kjems, J. & Valero, J. (2024). A Multi-Faceted Binding Assessment of Aptamers Targeting the SARS-CoV-2 Spike Protein. International Journal of Molecular Sciences , 25(9), Article 4642. https://doi.org/10.3390/ijms25094642

Dinesen, A., Andersen, V. L., Elkhashab, M., Pilati, D., Bech, P., Fuchs, E., Samuelsen, T. R., Winther, A., Cai, Y., Märcher, A., Wall, A., Omer, M., Nielsen, J. S., Chudasama, V., Baker, J. R., Gothelf, K. V., Wengel, J., Kjems, J. & Howard, K. A. (2024). An Albumin-Holliday Junction Biomolecular Modular Design for Programmable Multifunctionality and Prolonged Circulation. Bioconjugate Chemistry, 35(2), 214-222. https://doi.org/10.1021/acs.bioconjchem.3c00491

Westberg, M., Su, Y., Zou, X., Huang, P., Rustagi, A., Garhyan, J., Patel, P. B., Fernandez, D., Wu, Y., Hao, C., Lo, C. W., Karim, M., Ning, L., Beck, A., Saenkham-Huntsinger, P., Tat, V., Drelich, A., Peng, B. H., Einav, S. ... Lin, M. Z. (2024). An orally bioavailable SARS-CoV-2 main protease inhibitor exhibits improved affinity and reduced sensitivity to mutations. Science Translational Medicine, 16(738), Article eadi0979. https://doi.org/10.1126/scitranslmed.adi0979

Kang, H., Niu, L., Zhang, F., Qing, C., Dong, M., Guan, L., Zhang, M. & Liu, Z. (2024). A Novel Piezoelectric Nonwoven Fabric for Recoverable High-Efficiency Filters. ACS Applied Materials and Interfaces, 16(40), 54566-54573. https://doi.org/10.1021/acsami.4c10922

Vallina, N. S., McRae, E. K. S., Geary, C. & Andersen, E. S. (2024). An RNA origami robot that traps and releases a fluorescent aptamer. Science Advances, 10(12), Article eadk1250. https://doi.org/10.1126/sciadv.adk1250

Cao, W., Xia, D., Zhou, L., Liu, Y., Wang, D., Liang, C. & Chen, M. (2024). Antibacterial and antioxidant wound dressings with pH responsive release properties accelerate chronic wound healing. Materials Today Physics, 40, Article 101316. https://doi.org/10.1016/j.mtphys.2023.101316

Otzen, D. E. (2024). Antibodies and α-synuclein: What to target against Parkinson's Disease? Biochimica et Biophysica Acta - Proteins and Proteomics, 1872(2), Article 140943. https://doi.org/10.1016/j.bbapap.2023.140943

Westensee, I. N., Thomsen, K. L., Mookerjee, R. P. & Stadler, B. M. (2024). Antioxidant Microgels Support Peroxide-Challenged Hepatic Cells. Advanced Biology, 8(4), Article e2300547. https://doi.org/10.1002/adbi.202300547

Westensee, I. N., Paffen, L., Pendlmayr, S., Andres, P. D. D., Ramos Docampo, M. A. & Stadler, B. M. (2024). Artificial Cells And HepG2 Cells in 3D Bioprinted Arrangements. Advanced Healthcare Materials, 13(12), Article 2303699. https://doi.org/10.1002/adhm.202303699

Søgaard, A. B., Skovbo, F., Tvilum, A., Hansson, R. F. & Zelikin, A. N. (2024). Artificial Internalizing Receptor Affords Fast, Potent, Specific Drug Delivery to the Chemically Engineered Cells. Advanced Functional Materials, 34(33), Article 2400048. https://doi.org/10.1002/adfm.202400048

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Kalinka Hansen