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AUNAB - Aarhus University Network on Artificial Biology

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Recent research news on Artificial Biology

Actin-Powered Motors Build Cytoskeletons in Artificial Cells

AUNAB members Assistant Prof. Miguel Ramos Docampo's and Prof. Brigitte Stadler's effort to engineered artificial cells to form cytoskeleton-like networks using nanomotor-driven actin polymerization is published in ACS Nano. These hybrid vesicles merge active matter with synthetic biology to achieve life-like movement and self-organization inspired by Listeria’s actin-based propulsion.

16 October 2025 by Emilia Djomina Hansen

Read the article published in ACS Nano here.

Contact information:
Professor Brigitte Maria Städler
Aarhus University
Interdisciplinary Nanoscience Center (iNANO)
Email: bstadler@inano.au.dk

Assistant Professor Miguel Alexandre Ramos Docampo
Aarhus University
Interdisciplinary Nanoscience Center (iNANO)
Email: miramos@inano.au.dk

Recent publications by network

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Fabbrizio, P., Baindoor, S., Margotta, C., Su, J., Morrissey, E. P., Woods, I., Hogg, M. C., Vianello, S., Venø, M. T., Kjems, J., Sorarù, G., Bendotti, C., Prehn, J. H. M. & Nardo, G. (2025). Protective role of Angiogenin in muscle regeneration in amyotrophic lateral sclerosis: Diagnostic and therapeutic implications. Brain Pathology, 35(4), Article e13328. https://doi.org/10.1111/bpa.13328

Langmüller, A. M., Haller, B. C., Nolte, V. & Schlötterer, C. (2025). Purifying selection shapes the dynamics of P-element invasion in Drosophila simulans populations. Genome Biology, 26(1), Article 221. https://doi.org/10.1186/s13059-025-03688-2

Nowak, J. S., Kruuse, N., Rasmussen, H. Ø., Tian, P., Astono, J., Schultz-Nielsen, S., Thøgersen, M. S., Stougaard, P., Pedersen, J. S. & Otzen, D. E. (2025). Quaternary stabilization of a GH2 β-galactosidase from the psychrophile A. ikkensis, a flexible and unstable dimeric enzyme. Protein Science, 34(5), Article e70141. https://doi.org/10.1002/pro.70141

Brun, M., Hirsch, C. P., Juhász, P. & Otto, M. (2025). Random Connection Hypergraphs. https://arxiv.org/pdf/2407.16334

Pedersen, A. B., Andersen, D. G., Jakobsen, J. H., Montasell, M. C. & Zelikin, A. N. (2025). Receptor-Mediated Transmembrane Activation of Protein Folding in Synthetic Cells. Bioconjugate Chemistry, 36(4), 782-791. https://doi.org/10.1021/acs.bioconjchem.5c00043

Skovborg, G., Svejsø, F. H., Müller, C., Jensen, B. N., Jensen, J. G., Majidi, S. E., Matthiesen, C. L. & Chen, M. (2025). Replication of patient specific circulating tumor cells on a microfibrous filter for drug screening. Nanoscale, 17(18), 11592-11604. https://doi.org/10.1039/d4nr05294c

Golan, N., Parizat, A., Tabachnikov, O., Barnea, E., Olsen, W. P., Otzen, D. E. & Landau, M. (2025). Resilience and Charge-Dependent Fibrillation of functional amyloid: Interactions of Pseudomonas Biofilm-Associated FapB and FapC Amyloids. The Journal of Biological Chemistry, 301(2), Article 108096. https://doi.org/10.1016/j.jbc.2024.108096

Jiang, Y. & Kjems, J. (2025). RNA denaturation underlies circular RNA separation. Nucleic Acids Research, 53(21), Article gkaf1160. https://doi.org/10.1093/nar/gkaf1160

Nowak, J. S., Olesen, S., Tian, P., Bærentsen, R. L., Brodersen, D. E. & Otzen, D. E. (2025). Role of electrostatics in cold adaptation: A comparative study of eury- and stenopsychrophilic triose phosphate isomerase. Biochimica et Biophysica Acta - Proteins and Proteomics, 1873(4), Article 141072. https://doi.org/10.1016/j.bbapap.2025.141072

Kristoffersen, E. L., McRae, E. K. S., Sørensen, N. R., Holliger, P. & Andersen, E. S. (2025). Roles of dimeric intermediates in RNA-catalyzed rolling circle synthesis. Nucleic Acids Research, 53(11), Article gkaf057. https://doi.org/10.1093/nar/gkaf057

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Kalinka Hansen