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What is target validation?

A critical point in the development of new drugs is the transition from animal model systems to human testing, and both therapeutic failure and off-target effects are common reasons for development failure. Animal experiments are also both financially burdensome and time consuming.

ODIN projects will address these difficulties through the establishment of new human model systems. Moreover, ODIN aims to develop multiple screening methods for target validation. This can be achieved by ODIN through the inherent close collaboration with industry, thus creating synergies to speed up and enhance precision in drug development. 

Why does ODIN focus on target validation?

The different screening methods for target validation will greatly improve testing of drug precision while also speeding up drug development. This will give important insights into targets and improved understanding of diseases of interest, which in turn will lower the barrier to drug development.