Meet the FRIGG team
Chronic kidney disease (CKD) is a growing cause of global mortality. Yet, pre-clinical research and drug development are hampered by the lack of good translational CKD models and clinically-relevant biomarkers. By combining the expertise of several academic and industrial partners, the FRIGG project aims to model early stages of human CKD development in order to identify both novel CKD biomarkers as well as therapeutic targets; and to evaluate translatability. Below you can read more about the FRIGG team members
RIKKE NØRREGAARD - Associate Professor, Department of Clinical Medicine at Aarhus University:
Rikke has a background in biomedicine and is an expert in renal (patho)physiology. Her role in the FRIGG project will be to coordinate the translational studies related to CKD pathogenesis.
LENE N. NEJSUM - Associate Professor, Department of Clinical Medicineat Aarhus University:
Lene has a background in molecular medicine and works on the forefront of high-resolution bioimaging, with a special focus on renal physiology and kidney diseases. In the FRIGG project she will coordinate the identification and validation of novel CKD biomarkers using advanced bioimaging.
LIN LIN - Associate Professor, Department of Biomedicine at Aarhus University
Lin has a background in molecular biology and has extensive experience with the application of advanced genomic analysis technologies to elucidate disease processes and for the identification of therapeutic targets. Within the FRIGG project, she will coordinate the identification of new therapeutic targets using various OMICS platforms.
HENRICUS A. M. MUTSAERS - Assistant Professor, Department of Clinical Medicine at Aarhus University:
Rick is a biomedical scientist who has made major contributions to the development of novel drug‐screening platforms based on human tissue slices. At Aarhus University, he initiated a translational research line focusing on inter‐organ signaling networks in chronic diseases. In this project, he will oversee the studies with (human) precision-cut tissue slices.
https://www.linkedin.com/in/rickmutsaers/
MIA GEBAUER MADSEN - Chief Physician, Department of Urology at Aarhus University Hospital
ANNA KRARUP KELLER - Clinical Associate Professor, Department of Urology at Aarhus University Hospital
Mia and Anna will be responsible for the enrolment of patients.
https://www.linkedin.com/in/annakrarupkeller/
GITTE ALBINIUS PEDERSEN - Postdoc, Department of Clinical Medicine at Aarhus University:
Gitte has a background in molecular medicine and is well-versed in advanced fluorescence microscopy. In the current project, she will perform (fluorescence) microscopy and image analysis of human precision-cut tissue slices.
CAMILLA MERRILD - Research assistant, Department of Clinical Medicine at Aarhus University.
Camilla recently obtained her MSc degree in Molecular Medicine at Aarhus University. Within the FRIGG project, she will perform experiments with precision-cut kidney slices, in close collaboration with technician Gitte Skou.
JØRGEN KJEMS - Professor, iNANO and Department of Molecular Biology and Genetics at Aarhus University:
Jørgen will search for novel CKD biomarkers using the recently developed APTA-SHAPE technique.
AstraZeneca
PERNILLE LÆRKEGAARD HANSEN, SHRIKANT R. MULAY, LIHUAN LIANG and TIMO HASCHLER
Pernille B. Lærkegaard Hansen is Professor and Executive Director, Head of Bioscience Renal, Shrikant R Mulay is Director, Timo Haschler and Lihuan Liang are Senior Scientists in Bioscience Renal within Early Cardiovascular, Renal and Metabolism research and Development. AstraZeneca will support the FRIGG workstream by carrying out mass spectrometric analyses of precision-cut kidney slices to identify novel translatable pathways and targets that drive CKDPernille B. Lærkegaard Hansen is Professor and Executive Director, Head of Bioscience Renal, Shrikant R Mulay is Director, Timo Haschler and Lihuan Liang are Senior Scientists in Bioscience Renal within Early Cardiovascular, Renal and Metabolism research and Development. AstraZeneca will support the FRIGG workstream by carrying out mass spectrometric analyses of precision-cut kidney slices to identify novel translatable pathways and targets that drive CKD.
linkedin.com/in/pernille-b-laerkegaard-hansen-80678b10
linkedin.com/in/timonicolashaschler
Nordic Bioscience
FEDERIVA GENOVESA, DANIEL GULDAGER KRING RASMUSSEN and ALEXANDRA LOUISE MØLLER
Federica Genovese is a director of Fibrosis, Renal and Cardiovascular Research and Daniel Guldager Kring Rasmussen is Team Leader of Renal Research. Alexandra Louise Møller is a PhD student at Nordic Bioscience. Her research project is on biomarkers of ECM remodeling for complication of diabetes and preclinical models of kidney fibrosis. In this project, they will be responsible for the evaluation of extracellular matrix remodeling in the PCKS cultures, using Nordic Bioscience proprietary biomarkers of tissue remodeling.
https://www.linkedin.com/in/genovesefederica/
https://www.linkedin.com/in/daniel-g-k-rasmussen-phd-76244a47/
https://www.linkedin.com/in/alexandra-louise-m%C3%B8ller-21b872195/
Novo Nordisk
AGNèS BèRNADEAU, PETER HELDING KVIST and MARIA OUGAARD
Agnès Bénardeau is senior director of Cardio-renal biology and Peter Helding Kvist is director of Pathology & Imaging department at Novo Nordisk A/S, supporting the project pipeline with histological and pathological support. Specifically, target discovery and validation is performed for early projects at Novo Nordisk using state of the art technologies. Recently, spatial transcriptomics has been added to the portfolio of techniques analysing gene expression in human diseases like NASH, CVD and chronic kidney diseases. The team also includes research scientist Maria Ougaard whose expertise covers in vivo pharmacology in models of CKD and spatial transcriptomics to support to this project.