Latest news and events

Latest News from the Partnership

Photo: Joseph Chan/Unsplash

2021.04.20 | People

Three NCMM research groups extended for a further four years

Following a successful evaluation by NCMM’s Scientific Advisory Board (SAB), the NCMM Board has decided to extend the groups of Irep Gözen, Nikolina Sekulic, and Anthony Mathelier

Professor Janna Saarela in the Next Generation Sequencing Room at FIMM, University of Helsinki. Photographer: Kai Lindqvist

2021.04.19 | Research news

Immune cells out of control: how lethal hyperinflammation emerges from a novel gene defect

An international research team has discovered a novel subtype of a genetic immune deficiency disease. A genetically determined deficiency of the protein RhoG abrogates the normal killing function of specific immune cells, causing an uncontrolled inflammatory reaction called hemophagocytic lymphohistiocytosis (HLH).

GlyT1 (light blue) is a protein that transports glycine across the cell membrane (grey). To do this, it opens to the outside and inside of the cell alternately. In contrast to other neurotransmitter transporters, it is bound by its inhibitor (orange) from the intracellular side, rather than the extracellular one. The sybody, a synthetic mini-antibody (dark blue), also inhibits GlyT1 by binding to a novel extracellular site. Credit: Azadeh Shahsavar/DANDRITE

2021.04.08 | Research news

New perspectives for treating psychiatric disorders

Scientists at DANDRITE and EMBL Hamburg have determined the structure of Glycine Transporter 1. The finding could open new avenues for developing therapeutics for psychiatric disorders.

Plamena Markova. Photo: EMBL

2021.04.06 | People

International relations and their role in research at EMBL

Plamena Markova, Head of International Relations at EMBL, shares some insight into her role and how politics goes hand in hand with enabling scientific research.

The FIMM NGS Sequencing Laboratory. Photo: FIMM/University of Helsinki

2021.03.29 | Research news

Problems with cell’s skeleton and energy production: how a single gene defect can affect both neuronal development and immune system function

Researchers in Finland and Norway have discovered a gene defect that causes a novel inherited immune deficiency. The same gene, DIAPH1, has been previously shown to cause SCBMS syndrome, a rare genetic disease associated with severe brain development defects.

Cervical cancer cells. Photo: Sebastian Condrea

2021.03.19 | Research news

AI sup­por­ted diagnostics can fa­cil­it­ate screen­ing for cer­vical cancer in re­source-poor set­tings

A new study from FIMM group leader, Johan Lundin, at the University of Helsinki and Karolinska Institutet shows that artificial intelligence-supported digital microscopy at the point-of-care can be used to identify atypical Pap smears in a resource-limited setting.

Himanshu Sharma in the Umeå cryo-EM facility. Photo by Kai Ehrenbolger

2021.03.03 | People

Prestigious postdoctoral fellowship for structural biology and infection research in Umeå

Congratulations to Himanshu Sharma, a postdoctoral researcher in the Barandun Lab at MIMS & the Department of Molecular Biology, Umeå University on receiving a prestigious Marie Skłodowska-Curie Actions (MSCA) Individual Fellowship.

Photo: Colourbox

2021.03.02 | People

Norway's EMBL delegates, past and present

The EMBL (European Molecular Biology Laboratory) Council helps to guide EMBL's operations, administratively and scientifically.

Image: Pixabay/Gerd Altmann

2021.03.01 | Research news

Children and brain tumours: In search of a cure

Blog by NCMM group leader, Dr Sebastian Waszak: Whilst there has been good progress in treating many types of childhood cancer, some remain incurable. New precision medicine approach offers hope for young patients diagnosed with a rare and incurable brain tumour.

AI. Image: pexels.com
Breast Cancer Cells: Dr. Cecil Fox, Public domain, via Wikimedia Commons

2021.02.19 | Research news

AI pre­dicts ef­fic­acy of breast cancer treat­ment dir­ec­tly from tu­mor ar­chi­tec­ture

Researchers from the University of Helsinki have demonstrated the possibilities of artificial intelligence-based algorithms in predicting the efficacy of a targeted cancer therapy based on the tumour tissue architecture only, without specific molecular tests.

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Upcoming Partnership Events

Wed 05 May
10:00-15:00 | Oslo (Zoom)
NCMM Network Meeting
The NCMM Network Meeting 2021 is open to NCMM Associate Investigators and NCMM group leaders. The meeting will take place online.
Tue 25 May
09:00-09:34 | Oslo, Norway, and online
6th NorMIC Imaging Workshop
Course in Advanced Light Microscopy and Image Processing, hosted by University of Oslo
Mon 06 Sep
16:00-14:00 | Aarhus
Annual Nordic EMBL Partnership Network Meeting
Hosted by DANDRITE. Further details to follow.

News on publications

2021.02.01 | Publication

Cryo-EM structure of Helicobacter pylori urease with an inhibitor in the active site at 2.0 Å resolution

The Luecke Group at NCMM have published in the journal Nature Communications

2021.02.01 | Publication

Binocular integration of retinal motion information underlies optic flow processing by the cortex

Rune Nguyen Rasmussen and Akihiro Matsumoto et al. from Keisuke Yonehara’s lab have published in Current Biology.

Journal cover - featuring imagery from Irep Gözen.

2020.11.26 | Publication

Biological lipid nanotubes and their potential role in evolution

Research from the Gözen group at NCMM published in The European Physical Journal Special Topics.

Illustration by Björn O. Schröder

2020.09.10 | Publication

New publication from MIMS group leader Björn O. Schröder in JBC on function of microbiota in obese mice

The paper, 'Obesity-associated microbiota contributes to mucus layer defects in genetically obese mice', has been published in the Journal of Biological Chemistry.

Illustration by Barbara S. Sixt, showing a viable cell infected with Chlamydia, which reside in a vacuole inside the host cell. Due to the occuring cell death, the host cell dies and releases the bacteria.

2020.09.10 | Publication

A high profile review article from MIMS group leader Barbara S. Sixt on host cell death modulation by the bacterial pathogen Chlamydia

The review has been published in the journal FEMS Microbiology Reviews.

2020.09.02 | Research news, Publication

Comment article: Predicting Cancer Evolution Using Cell State Dynamics

Dr Kuijjer's article, 'Predicting Evolution Using Cell State Dynamics', examines research using state transitions to model cancer development and progression.

Protocells. Image: Advanced Science News

2020.09.02 | Publication

Rapid Growth and Fusion of Protocells in Surface‐Adhered Membrane Networks

Elevated temperatures might have promoted the nucleation, growth, and replication of protocells on the early Earth.

The scheme shows the TRACE method that labels active inputs to a specific brain area through a retrograde labelling activity depended viral approach. Credit: First author Nathalie Krauth

2020.05.14 | Knowledge exchange, Publication

Joint efforts between Nabavi and Capogna group have led to the development of a novel approach named TRACE ´Tracing Retrogradely the Activated Cell Ensemble’

The neural circuitry teams at DANDRITE and PROMEMO introduce a novel approach in their latest publication, which selectively labels sensory inputs that are activated by a defined stimulus and directed to a region of interest in the brain.

Photo: Manuel Rivas, Adapted from image by Lauren Solomon, Broad Communications

2020.05.06 | Publication, Knowledge exchange

Gene vari­ants that pro­tect against glauc­oma iden­ti­fied, open­ing thera­peutic pos­sib­il­it­ies

An international research collaboration led by researchers from the University of Helsinki and Stanford University has identified rare changes in a gene called ANGPTL7 that lower intraocular pressure and significantly reduce the risk of glaucoma. The results open important new therapeutic possibilities.

The zebrafish facility, NCMM. Photo: Øyvind Eide.

2020.04.24 | Publication, Knowledge exchange

New work from the Esguerra group provides novel insight into disease mechanisms of Dravet syndrome

A new article from NCMM’s chemical neuroscience group published in Epilepsia sheds light on the early mechanisms underlying seizure onset in Dravet syndrome, a severe and devastating type of epilepsy that occurs in children and infants.

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