Latest news and events

Latest News from the Partnership

Photo: Christine Panagiotidis

2019.10.09 | People , Events

Science by the Seafront: researchers from around the world connected at the annual EMBL Partnership Conference “Perspectives in Translational Medicine”.

Hosted by EMBL Barcelona, located at the Barcelona Biomedical Research Park, the 3rd annual EMBL Partnership Conference took place from 25-27 September in Barcelona, Spain.

Photo: Dr Elisabeth Widén. Credits: Centre of Excellence in Complex Disease Genetics, University of Helsinki

2019.09.09 | People , Research news

Elisabeth Widén, Group Leader, FIMM

Dr Widén is a physician by training, with an interest in genomics and the genetic contribution to complex diseases. Dr Widén initially focused her research on puberty and the genes that influence this process. In recent years, however, Dr Widén’s interest has now shifted towards implementing genomic research into medical practice.

Professor Mark Joseph Daly

2019.09.02 | People , Awards

Honorary doctorate 2019: Professor Mark Joseph Daly

Professor Mark Joseph Daly, Director of the Institute of Molecular Medicine Finland (FIMM), the Finnish node of the Nordic EMBL Partnership is awarded Aarhus University’s honorary doctorate at the Faculty of Health.

The Nabavi Group. Credits: Susanne S. Sjøgaard
Dr. Sadegh Nabavi and a two-photon microscope to visualise neural communication. Credits: Susanne S. Sjøgaard

2019.08.21 | People , Research news

Behind the Scenes: Dr Sadegh Nabavi, Group Leader at DANDRITE

Nabavi’s group focuses on memory formation and consolidation at the synaptic and circuit levels. Recently, Dr. Sadegh Nabavi had his group leader position extended for a further four years. In our latest Behind the Scenes article, Dr Nabavi discusses his research and his curiosity and passion for neuroscience.

2019.08.20 | News from the management, People

15 exciting PhD positions as part of PROTON, a collaborative effort of 10 academic and 2 industrial partners, are now available.

PROTON is funded by the prestigious Horizon 2020-MSCA-ITN European training Network grant. The goal is to jointly train 15 PhD students in the field of proton transport and proton coupled transport. Two of the positions will be based with Professor Hartmut Luecke’s group at NCMM.

The figure (A-D) illustrates the process from raw electron micrographs showing individual protein molecules (green boxes) to the building of a protein model. Image by Milena Timcenko

2019.08.01 | People , Research news, Publication

Researchers at DANDRITE and collaborative partners have used cutting-edge electron microscopy to reveal the first structures of the P4-ATPase lipid flippase; a crucial protein for cell viability

PhD-student Milena Timcenko and Assistant Professor Joseph A. Lyons give an insight into their recently published article in the renowned journal Nature “Structure and autoregulation of a P4-ATPase lipid flippase”.

Dr. Irep Gözen. Photo by Oda Hveem
PhD student Elif Köksal. Photo by Kristin Ellefsen
Photo: Spontaneously formed protocells, which resemble balloons anchored to a surface by a network of nanotubes. Image is visualized by 3D confocal microscopy by Elif Köksal.

2019.07.26 | People

NCMM-EMBL Group Leader Irep Gözen works within chemical life sciences, bionanotechnology and membrane systems

Dr. Irep Gözen has a PhD in chemistry from the Chalmers University of Technology, Sweden, and was previously a postdoctoral researcher in Professor Vinothan Manoharan’s group at Harvard University. She joined NCMM as head of the Bionanotechnology and Membrane Systems Group in 2016. She also holds an adjunct associate professor position at the…

2019.07.09 | News from the management, People

Group Leader position at NCMM

NCMM offers a Group Leader position with a start-up package in Precision Medicine

Dr Ellen Bushell. Photo: MIMS

2019.07.02 | People

Introducing MIMS-EMBL Group Leaders: Ellen Bushell - Parasite-host interactions that govern malaria infection and disease

Dr Bushell, who is originally from Umeå, joined MIMS as a group leader from the Wellcome Sanger Institute near Cambridge in Autumn of 2018

Dr Johan Henriksson. Image: MIMS

2019.06.25 | People

Introducing MIMS-EMBL Group Leaders: Johan Henriksson - T cell Systems Biology

Dr Johan Henriksson, who is originally from Sweden, joined MIMS in April 2019. His group mainly focuses on the quantitative analysis of gene regulatory networks. He works with advanced computer modelling to try and build an overall understanding into how genes are interconnected

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Upcoming Partnership Events

Mon 11 Nov
09:00-13:00 | Oslo Science Park, Oslo, Norway
NCMM PhD course
PhD course in Molecular Medicine
Thu 28 Nov
09:00-16:00 | EMBL Heidelberg
EMBL PhD Symposium
The symposium aims to promote interdisciplinary exchange among the next generation of life scientists.

News on publications

(A) Schematic of the “space-time wiring” model. The input unit at the preferred side (Unit 1, blue) has slower kinetics than the unit at the null side (Unit2, magenta). (B) The offset of synaptic delay across input units in the preferred direction: the earlier but delayed input from Unit1 is integrated effectively with the later but fast input from Unit2. During null-direction motion, the offset mechanism does not work.  
The discovered 6 subgroups of glutamate inputs (G1-G6, coloured circles) to ON DS cells. The 6 groups have different temporal kinetics (fast/slow; transient/sustained) and spatially organized.

2019.10.14 | Publication, Research news, Knowledge exchange, People

Yonehera group at DANDRITE have identified a new circuit mechanism in mammalian retinal motion computation

Latest research from the group led by Keisuke Yonehara at DANDRITE has recently been published in peer-reviewed scientific journal “Current Biology”. The study is about the space-time wiring between a type of motion-sensitive cells that project to the brain for gaze stabilization and local excitatory cells in the mouse retina.

First author of the paper Ahmad Ali-Ahmad at work in the lab. Photo: Nadia Frantsen
Group leader Nikolina Sekulic. Photo: Oda Hveem
Illustration showing the effect of CENP-C binding to CENP-A nucleosomes. Further details can be found in the full article (link at the bottom of this page).

2019.09.11 | Publication, Research news

Research from the Sekulic Group provides new molecular insights into the structure and function of the centromer

New work from the group led by Nikolina Sekulic at NCMM has been published in EMBO Reports. The study sheds light on the structure of nucleosomes contained within the centromere; findings that will help to improve our understanding of the important molecular events that drive cell mitosis.

Dr. Jonas Barandun
Light microscopy image of microsporidian spores of Vairimorpha necatrix. Picture by Charles Vossbrinck
a) The cryo-EM density of the microsporidia ribosome solved by Jonas Barandun and his colleagues. The large ribosomal subunit is colored in shades of blue and green while the small ribosomal subunit is colored in shades of yellow and orange. Novel identified factors MDF1 and MDF2 are labeled. b) The microsporidia ribosomal RNA compared with yeast rRNA. The bar to the right compares the stretched RNA in length. c) A comparison of ribosomal structures of the microsporidium V. necatrix (to the right) with selected structures from major branches of the tree of life. Organism names are indicated below (P. falciparum: Malaria parasite, H. sapiens: human, S. cerevisiae: yeast, fungi). Ribosomal RNAs are depicted in light-blue (LSU, large subunit) and yellow (SSU, small subunit). Elements that are not present in microsporidia are colored in orange and dark-blue. Illustration by Jonas Barandun

2019.07.28 | Publication

Miniaturized version of ribosome found in microsporidia

A research team lead by MIMS/SciLifeLab research group leader Jonas Barandun uses cryo-electron microscopy to provide near atomic details of the smallest known eukaryotic cytoplasmic protein synthesis machine, the microsporidian ribosome.

2019.06.13 | Publication

DrugComb, a one-stop solution to all your cancer drug combination data analysis needs

Assistant Professor Jing Tang, a principal investigator of the Network Pharmacology group at FIMM and at the UH Faculty of Medicine has led the development of DrugComb, an open resource for harmonizing cancer drug combination studies. Dr. Tang hopes that DrugComb would become a collaborative data analysis platform that would bring forth more…

2019.03.15 | Publication

Drug combination sensitivity scoring facilitates the discovery of synergistic and efficacious drug combinations in cancer.

The study was conducted by research groups lead by Jing Tang at the Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE) and the Faculty of Medicine and Caroline Heckman at FIMM. The results were recently published in PLOS Computational Biology.