Core Facilities

These core facilities serve researchers from both within and outside an institution. They are all open to use by researchers at each node, and some are open to researchers from outside the Partnership.

DANDRITE

The JOINT

The JOINT is an interactive workshop facility based at the Department of Biomedicine, Aarhus University, for neuro-scientific research using electrophysiology, optogenetics, and behavioral experimental set ups.

Read more.

FIMM

Genotyping Unit

The Genotyping Unit at FIMM provides SNP Genotyping and CNV analysis, DNA methylation analysis, Cell line authentication and Mouse speed congenics SNP genotyping.

Read more.

Bioinformatics Unit

The Bioinformatics Unit offers a comprehensive bioinformatics service to help analyze data. Services include, genomics, next-generation sequencing and high-throughput screening. The unit can also integrate data from multiple sources, such as reference databases, to extract knowledge from the data.

Read more. 

Digital Microscopy and Molecular Pathology Unit

The Digital Microscopy and Molecular Pathology Unit provides high throughput whole-slide scanning services for all customers. The unit offers quick, high-quality and cost-efficient wide-field microscope imaging for bright field and fluorescence.

Read more.

Extracellular Vesicles Core

Extracellular Vesicles (EV) Core is the world’s first technology platform dedicated to Extracellular Vesicle isolation and analytics. The EV Core is divided into two units. EV Core FIMM focuses on EVs from liquid biopsy samples, including isolation and analysis of EV-RNA as well as electron microscopy samples. EV Core Viikki is dedicated to the characterization of EVs using NTA and Apogee micro flow cytometer, and functional assays.

Read more. 

High Content Imaging and Analysis

FIMM High Content Imaging and Analysis (FIMM-HCA) provides automated high-content screening microscopes (a spinning-disk confocal with live imaging option and a widefield) for imaging and guidance for image analysis and data management.

Read more. 

Information Technology Unit

The IT Unit has 1500 CPU computing cluster for analysis, and over a hundred physical and virtual servers hosting bioinformatics applications and databases vital for biomedical research.

Read more

Metabolomics/Lipidomics/Fluxomics

The FIMM Metabolomics/Lipidomics/Fluxomics Unit offers services to researchers in many diverse scientific fields, such as high-throughput mass spectrometry-based targeted quantitative and global metabolomics/lipidomics and fluxomics services to basic, biomedical, preclinical and clinical researchers.

Read more.

Sequencing Unit

The Sequencing Unit provides state-of-the-art DNA sequencing services. Its platforms enable a wide range of sequencing applications from massive genome scale analysis to rapid targeted experiments of selected genomic regions.

Read more. 

High Throughput Biomedicine Unit

The High Throughput Biomedicine Unit (HTB) provides high throughput screening approaches of many types, such as Drug Sensitivity and Resistance testing (DSRT assay), siRNA screening, Cell-based and biochemical screens, Molecular probe discovery, Biological profiling using libraries of known bioactives, Drug repositioning, and Personalized medicine screening (drug resistance and sensitivity) using approved and investigational drugs. 

Read more. 

Single Cell Analytics

FIMM Single Cell Analytics (SCA) unit develops and provides single cell transcriptomics services nationally and internationally. FIMM SCA unit is part of Helsinki Institute of Life Science (HiLIFE) Single-Cell omics (SC Omics) network. SCA is closely collaborating with the Sequencing Unit at FIMM.

Read more.

MIMS

Biochemical Imaging Centre Umeå

The Biochemical Imaging Centre Umeå, was founded with support from the Swedish Research Council in order to establish a node of excellence for fluorescence super-resolution and live cell imaging. The centre includes equipment for combined use of different advanced imaging techniques to visualise the same sample in multiple ways. Instrumentation includes a spinning disk microscope and a confocal microscope with resonant scanner. Both microscopes are fully equipped for photo-bleaching (FRAP) and photo-quenching (FRET) experiments and TIRF (total internal reflection fluorescence) microscopy. The equipment is completed with a STORM-unit that allows super-resolution imaging of structures and micromanipulators down to 20nm. 

Read more. 

Umeå Core Facility for Electron Microscopy

UCEM provides instruments and methods in Transmission Electron Microscopy (TEM) and Scanning Electron Microscopy (SEM) as a national research infrastructure. UCEM is an interdisciplinary multifunctional core facility for advanced electron microscopy (EM). The SEMs , Merlin and Evo, offer high-resolution surface imaging. With a great configuration of multiple detector systems operating under cryo, room temperature or heated conditions. Correlative Light and Electron Microscopy (CLEM) targeted Shuttle & Find provides a solution for finding the precise location of a target proteins or labeled structure of interest in a large area, simplifying high-precision localization and high-resolution imaging of the same sample.

Read more.

NMR Core Facility at Umeå University

The KBC Core Facility for NMR provides access to state-of-the-art NMR equipment and expertise. Besides studies of soluble proteins and other biomolecules at 850 and 600 MHz, this infrastructure offers nationwide also unique solid-state NMR equipment at 850 and 500 MHz for studies of membrane proteins & amyloid fibrils, metabolomics on intact tissues, environmental NMR and fragment-based screening and is a national support for the Chemical Biological Consortium Sweden (CBCS). High-field instruments are equipped for biomolecular solution NMR, robotic sample preparation and high-throughput metabolomics of biofluids and even intact specimen.

Read more. 

NCMM

Chemical Biology Screening: High-Throughput Screening Platform (NCMM)

The Chemical Biology Screening unit enables researchers to discover small molecules to probe, explore and modulate biological systems through high-throughput screening of small molecules. It also providers assay development assistance and data management services.

Read more.

Zebrafish Facility (NCMM)

The zebrafish facility offers access to fish housing and breeding, as well as the use of several instruments for specific research on zebrafish. There are tanks for keeping zebrafish, and separate tanks for generating/regenerating fish lines. The facility also has tanks for breeding and three iSPAWN for large-scale production of synchronized eggs.

Read more. 

Biobank at FIMM
The FIMM Biobanking Facility.
Facilities at MIMS
Core facilities available at MIMS